Protein Info for ABIE40_RS04995 in Rhizobium sp. OAE497

Annotation: Na+/H+ antiporter subunit B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 139 transmembrane" amino acids 9 to 28 (20 residues), see Phobius details amino acids 34 to 55 (22 residues), see Phobius details amino acids 67 to 96 (30 residues), see Phobius details amino acids 111 to 133 (23 residues), see Phobius details PF04039: MnhB" amino acids 5 to 127 (123 residues), 107.5 bits, see alignment E=3e-35

Best Hits

Swiss-Prot: 31% identical to MNHB2_STAS1: Putative antiporter subunit mnhB2 (mnhB2) from Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)

KEGG orthology group: K05566, multicomponent Na+:H+ antiporter subunit B (inferred from 82% identity to rlg:Rleg_1001)

Predicted SEED Role

"Na(+) H(+) antiporter subunit B" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (139 amino acids)

>ABIE40_RS04995 Na+/H+ antiporter subunit B (Rhizobium sp. OAE497)
MNTLIFRTIAPFLTALMLLFSVFILLRGHNEPGGGFIGGLIAASALAIYGIANGVPAVRR
AIRFHPLAIAGTGLLMSSVAGLISIFAAVPFMTGLWIYPVILGIEVPLSSVMLFDFGVYF
VVLGAITAIALTLEEREVE