Protein Info for ABIE40_RS04990 in Rhizobium sp. OAE497

Annotation: putative monovalent cation/H+ antiporter subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 788 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 84 to 102 (19 residues), see Phobius details amino acids 113 to 130 (18 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 166 to 189 (24 residues), see Phobius details amino acids 210 to 233 (24 residues), see Phobius details amino acids 247 to 265 (19 residues), see Phobius details amino acids 277 to 295 (19 residues), see Phobius details amino acids 304 to 323 (20 residues), see Phobius details amino acids 330 to 351 (22 residues), see Phobius details amino acids 363 to 390 (28 residues), see Phobius details amino acids 411 to 432 (22 residues), see Phobius details amino acids 452 to 474 (23 residues), see Phobius details amino acids 500 to 521 (22 residues), see Phobius details amino acids 568 to 590 (23 residues), see Phobius details amino acids 605 to 623 (19 residues), see Phobius details amino acids 630 to 649 (20 residues), see Phobius details amino acids 655 to 677 (23 residues), see Phobius details amino acids 689 to 709 (21 residues), see Phobius details amino acids 749 to 766 (18 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 69 to 115 (47 residues), 44.8 bits, see alignment 1.9e-15 PF00361: Proton_antipo_M" amino acids 131 to 414 (284 residues), 217.5 bits, see alignment E=4.9e-68 PF13244: MbhD" amino acids 612 to 675 (64 residues), 63.4 bits, see alignment E=3.7e-21 PF20501: MbhE" amino acids 688 to 769 (82 residues), 74.1 bits, see alignment E=1.6e-24

Best Hits

KEGG orthology group: K05565, multicomponent Na+:H+ antiporter subunit A (inferred from 78% identity to rle:RL1372)

Predicted SEED Role

"Na(+) H(+) antiporter subunit A" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (788 amino acids)

>ABIE40_RS04990 putative monovalent cation/H+ antiporter subunit A (Rhizobium sp. OAE497)
MAGVTGLTFLALCLPFIGALAAPFAVRLFGANAAWLLALFPLLSFLHFLGFLPEIAAGEV
ATGGYVWVPSYNLSFSWFLDGLSLTFALLITGIGTLIVLYAGGYLKGHRDHGRFFSFIFL
FMGSMLGLVVSDSFLMLFIFWELTSITSFLLIGFDHEREAARRAALQALVVTGGGGLCLL
AGLLFIWNITGVTQLSLIMEAGDLMRESPFYLATLLLVLGGAFTKSAQFPFHFWLPNAME
APTPVSAYLHSATMVKAGVYLLLRLHPLLGETPAWEILLPFFGGMTLATGAALAIRQTDL
KLKLAYTTVSSLGLLVLLTGFGSEYAIEAAVLYLVAHSLFKGALFMVAGILDHETGTRDI
TRLSGLASAMPLTCAAALAAAFSMAGLPPFFGFLAKEEIYAALAIGDLRSIVFTSVAVFG
NALMFAIAFAVGLKPFIGKRSETPKPPHEAPVLLWIGPALLALLGFVAAIFSSSVHRYIS
TPMASAVEHRPVEITISLMPHIGVPLLLSVLTIALGIVIYFQLDRSRRLADAFFRAAGPG
PDTGFDIFISGLVRLAHRITGILQPGRLEIYVTATFILLAAILLVPLYLYGELPTGIAWP
DHVRLHEWAVLLLAVIGLAAVLTARDRLTAIAALGIQGLSVALIFLMFGAPDLAFTQFMV
ETLAVVILALVMTRLRLSPTDRRPRGQRLLDATIALACGLGLTLLLLRATSGRFDTALSD
FFNTYSKTIAHGTNVVNVIIVDFRGTDTLGEIAVVAIAALAIIALIRMRAGTERKLAPPD
PKQPGRGT