Protein Info for ABIE40_RS04145 in Rhizobium sp. OAE497

Annotation: zinc ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01297: ZnuA" amino acids 30 to 294 (265 residues), 281.1 bits, see alignment E=4.6e-88

Best Hits

Swiss-Prot: 31% identical to MTSA_LACLA: Metal ABC transporter substrate-binding lipoprotein (mtsA) from Lactococcus lactis subsp. lactis (strain IL1403)

KEGG orthology group: K02077, zinc/manganese transport system substrate-binding protein (inferred from 89% identity to rlg:Rleg_0678)

Predicted SEED Role

"Zinc ABC transporter, periplasmic-binding protein ZnuA" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>ABIE40_RS04145 zinc ABC transporter substrate-binding protein (Rhizobium sp. OAE497)
MLSRTLLLSAALPALLAASAIPASAETLKVVASFTVLADVVKQVGGDHVSVTSLVGPNGD
PHEFEPSPADAKHLKAAQVTFVSGEGLEGWMDRLITASGYKGTPVTASEGINTRTMEEDG
KTVTDPHVWNSPVNVKVWVVNIEKALSAADPADAAAFKTNADRYTKTLDELDAYAHSKFD
KVADDRRKVLTSHDAFGYFGREYQVSFLAPLGVSTESEASAADVAKLIEQIKAENVKTYF
FENSNDPRLVKQVAKATGAKPGGELYVESLSDAKGPAPTYEKMFRYNVDQIAAAMAKSS