Protein Info for ABIE40_RS01100 in Rhizobium sp. OAE497

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 PF00561: Abhydrolase_1" amino acids 57 to 150 (94 residues), 32.2 bits, see alignment E=3.7e-11 PF12697: Abhydrolase_6" amino acids 59 to 253 (195 residues), 52.6 bits, see alignment E=4e-17 PF12146: Hydrolase_4" amino acids 63 to 151 (89 residues), 40.1 bits, see alignment E=1.1e-13 PF07859: Abhydrolase_3" amino acids 91 to 157 (67 residues), 35.5 bits, see alignment E=3.8e-12 PF05728: UPF0227" amino acids 93 to 221 (129 residues), 25.2 bits, see alignment E=6.3e-09 PF05990: DUF900" amino acids 93 to 163 (71 residues), 20.6 bits, see alignment E=1.1e-07 PF00326: Peptidase_S9" amino acids 96 to 263 (168 residues), 26.2 bits, see alignment E=2.1e-09

Best Hits

KEGG orthology group: None (inferred from 76% identity to rle:RL0265)

Predicted SEED Role

"2-hydroxymuconic semialdehyde hydrolase (EC 3.1.1.-)" (EC 3.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.-

Use Curated BLAST to search for 3.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (267 amino acids)

>ABIE40_RS01100 alpha/beta hydrolase (Rhizobium sp. OAE497)
MSEMQNAPDPQFLSVGDGDASRQIAFILREASRAEGAPTLVWLSGYRSDMSGTKAIELDR
LAAEMGLACLRLDYSGHGLSGGEFRDGTISRWLEEALAVIHHANPKRIIVVGSSMGGWIA
LRLAQELGKHANGPKLDGMVLIAPAPDFTSDLIEPHLTKKERASLEERGYFEEKSEYSPE
PNIYTRALIDDGRANQVLTGIIETGCPVHILQGMKDPDVPYAHAMKLIEHLPSDDVVLTF
VRDGDHRLSRPQDIERMLAAVTALVRQ