Protein Info for ABID97_RS28855 in Variovorax sp. OAS795

Annotation: PAS domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 995 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 258 to 280 (23 residues), see Phobius details PF02743: dCache_1" amino acids 26 to 189 (164 residues), 50.4 bits, see alignment E=9.4e-17 PF00989: PAS" amino acids 332 to 439 (108 residues), 26.9 bits, see alignment E=1.9e-09 amino acids 455 to 562 (108 residues), 32.3 bits, see alignment E=3.9e-11 amino acids 579 to 678 (100 residues), 24.2 bits, see alignment E=1.3e-08 TIGR00229: PAS domain S-box protein" amino acids 334 to 449 (116 residues), 58.2 bits, see alignment E=9.4e-20 amino acids 452 to 572 (121 residues), 33.8 bits, see alignment E=3.4e-12 amino acids 573 to 696 (124 residues), 54.4 bits, see alignment E=1.3e-18 amino acids 697 to 821 (125 residues), 41.6 bits, see alignment E=1.2e-14 PF08448: PAS_4" amino acids 337 to 444 (108 residues), 44.2 bits, see alignment E=9.4e-15 amino acids 457 to 566 (110 residues), 28.1 bits, see alignment E=9.5e-10 amino acids 584 to 690 (107 residues), 73 bits, see alignment E=1e-23 amino acids 708 to 815 (108 residues), 48.9 bits, see alignment E=3.2e-16 PF13426: PAS_9" amino acids 340 to 441 (102 residues), 29.6 bits, see alignment E=3.2e-10 amino acids 463 to 563 (101 residues), 23.7 bits, see alignment E=2.2e-08 PF08447: PAS_3" amino acids 353 to 435 (83 residues), 30.5 bits, see alignment E=1.7e-10 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 823 to 985 (163 residues), 152.3 bits, see alignment E=9.9e-49 PF00990: GGDEF" amino acids 825 to 982 (158 residues), 157.6 bits, see alignment E=1.1e-49

Best Hits

KEGG orthology group: None (inferred from 89% identity to vap:Vapar_6160)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (995 amino acids)

>ABID97_RS28855 PAS domain-containing protein (Variovorax sp. OAS795)
MITALVLALVGATGWWQYRSLSSEYVNLMREQQQALTEGAAADLDYKLGVHLAALAHAAR
ELGEQGVSDPAAQQRFLADKELRTMFDNAALATLDGAIVAIAPPTAQPPNIADRDYFKRV
RDLRQPAISAPLLTKGGQQPAVVMAVPVETPDGRLAGVLGAALNLQRANVLGDLSRATVG
RGGYYEIVTRGESPRIVMHPDAKLLLKPAGAAAVAFDGDTGNDLATHATVRSADWDLRLI
VPARAAYAPLEQARRNLLLQLLWLGLGCALLVWLGTAWVMRPLESLSNAIRTLRHSPDSE
VKLDVVANDERGDLAREFDALMAELREQRLEVAAVTDASPVGLFRCDSSGCMTYVNDEYL
AIHGLAREDAQEGWLTLVREEIREKVRQDWIRLVNAEEPLNATRRLHRKDGTQVLVALRS
RPVIAEGRVQGHVGTVTDITERTRAERALRTLTAVFDMTTDYIVQLDAAGRVLYMNPAAR
RRTGIDAEAPVEQLSVADFNPPRTIERFRSEVVPTAMATGVWVGESMVWDARREEFPVSH
MVIAHRDKHGKVEYFSGLMRDISAAKAAEQALRDSEQRLRMVTDHLPALISYLDRDLRFR
FVNKAYQDWFGTVPERLLGRSLQEFYGDEAWAQMEPYIRAALGGRQVTYERRVTGPGGRR
DIQATLVPERNERGEVMGLYTLDSDITAHHEAEEALQESEARLRTVADALPMRVAYIDAD
ERYRFNNLAYEREFGLSRDQIQGHTVHELLGDPAYESVKPHIRAALAGEVVTFQSEVSQS
DSYNCYEAQYIPQSAANAETIVGFHAVITDITRQKLEEKRLVNLAQIDPLTGLANRAGFE
ARLAEAMDRSRSAGALMALMYLDIDGFKQINDQFGHQTGDELLKAFSNRLSQGLRSSDVR
ARLGGDEFTVIMEGLPHADIAVSAATKLVIAMQAPFGTEQRTIDVTASIGLAFYQGGTAT
AAALVRQADEMLYRAKRSGRNNVQAAALPIDSGLT