Protein Info for ABID97_RS28220 in Variovorax sp. OAS795

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 PF00106: adh_short" amino acids 12 to 201 (190 residues), 139.8 bits, see alignment E=1.2e-44 PF08659: KR" amino acids 15 to 171 (157 residues), 40.7 bits, see alignment E=3.7e-14 PF13561: adh_short_C2" amino acids 19 to 251 (233 residues), 189.1 bits, see alignment E=1.4e-59

Best Hits

Swiss-Prot: 44% identical to DECR2_PONAB: Peroxisomal 2,4-dienoyl-CoA reductase (DECR2) from Pongo abelii

KEGG orthology group: None (inferred from 96% identity to vap:Vapar_5766)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (272 amino acids)

>ABID97_RS28220 SDR family oxidoreductase (Variovorax sp. OAS795)
MDFSAFDFKGRHVAVAGGSSGINFGIAQAFARAGARLTVLSRSADKVAAAAQRLEALGTE
ALGIPADVRQPEALERAFAAGAERFGPIDVLVSGAAGNFLASALDMSPNAFKTVVDIDLL
GSFNVARLAHAHLRKPGACVIQISAGQAFTPTPFQAHVCAAKAGVDMLTQVLALEWGPQG
IRINSIVPGPIADTEGLKRLAPTDDTMAAMAQRVPLKRLGRIEDISRMAMMLASDWGSYI
TGAVIPVDGGLALTGPRDFTAAAAASKRGAAP