Protein Info for ABID97_RS27710 in Variovorax sp. OAS795

Annotation: Fe-Mn family superoxide dismutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02777: Sod_Fe_C
  • amino acids 93 to 190 (98 residues), 79.9 bits, E=1.3e-26
• PF00581: Rhodanese
  • amino acids 214 to 293 (80 residues), 36 bits, E=8.3e-13

Best Hits

KEGG orthology group: K04564, superoxide dismutase, Fe-Mn family [EC: 1.15.1.1] (inferred from 86% identity to vap:Vapar_5758)

Predicted SEED Role

"Superoxide dismutase [Mn] (EC 1.15.1.1)" in subsystem Oxidative stress (EC 1.15.1.1)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethene biosynthesis III (microbes) (6/7 steps found)
• superoxide radicals degradation (2/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.15.1.1

Use Curated BLAST to search for 1.15.1.1

Protein Sequence (308 amino acids)

>ABID97_RS27710 Fe-Mn family superoxide dismutase (Variovorax sp. OAS795)
MDVRIQPLPFDPAALPGLSERLLVSHYQNNYGGAVKRLNAIRAQLAATPPASTPGFQLNG
LKREELIANNSMLLHELYFASLGGHGEPMDPPMALALAASFGSVDRWREEFTAMGKALGG
GSGWVLLSFQPREGTLVNQWAADHTHALAGATPLLALDMYEHAYHLDHGAAAGAYVDAFM
DNIRWKQVYARYQQAVHAASEPFGATQDEIAGSLLLDVRRAGVFEQATALLPGARWFDPA
GVGSWAAELPPDRDVVVYCVYGHEVGRTTAMRLRAAGLNARYLLGGIDAWQAAGRPLEAK
PAGEKASA