Protein Info for ABID97_RS27700 in Variovorax sp. OAS795

Annotation: HAMP domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF00512: HisKA" amino acids 150 to 210 (61 residues), 39.7 bits, see alignment E=4e-14 PF02518: HATPase_c" amino acids 258 to 366 (109 residues), 66.2 bits, see alignment E=3.6e-22

Best Hits

KEGG orthology group: None (inferred from 49% identity to aav:Aave_3518)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (374 amino acids)

>ABID97_RS27700 HAMP domain-containing sensor histidine kinase (Variovorax sp. OAS795)
MRLAEFINIHSETIVAEAARYARTLAPLAHESELTLQDHIPKILEAIVLDLAHSQSSNEA
HAKSLGQGVILSSTVDSAAQTHGRQRARSGLQMTQLVAEYRALRAGVLRLWAENEPLAIP
VVDLIRFNEAIDQAVAESVEFFSEETDQLRNVFLGVLGHDLRGPLNAILLTAELISRKTK
ESPLSEVGVLIRSGRRMASLLDTLLQYNRSALGGGMKIHRELTNLGEQCAAEVELLRAAL
PDARIDFSAESDTEGLFDASAVREALGNLVNNAATYGDAGPVSVTLTGGVAAVSLKVANT
GPEIPSAEIPKLFKALQRGSMADTSGSHTNLGLGLFIVQQIVVAHGGQVRCVSSAAKTSF
ELEFPRAVAAQRAA