Protein Info for ABID97_RS26630 in Variovorax sp. OAS795

Annotation: aspartate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 36 to 455 (420 residues), 327.3 bits, E=1.2e-101

Best Hits

KEGG orthology group: K00843, [EC: 2.6.-.-] (inferred from 52% identity to sil:SPO2005)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

• biotin biosynthesis I (13/15 steps found)
• biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)

KEGG Metabolic Maps

• Biotin metabolism
• Ether lipid metabolism
• Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
• Vitamin B6 metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.-.- or 2.6.1.62

Protein Sequence (469 amino acids)

>ABID97_RS26630 aspartate aminotransferase family protein (Variovorax sp. OAS795)
MTTSNSQATGIARIGDEPRGGSVLGFYAPKGSARPPRIARGEGIFLWDANGKRYLDATAG
AVVANLGHGNPRVLAAMAEQASKVSFAYPRFFESEHNIALADRICELAGDGLDRAFFVSG
GSEANEAALKLARQYAVVTGQGTRWKVISRDPSYHGSTLGALAVTGDANTLQLYGPMIRS
MPKVPAPLSYRPPDGHTAESHEKACTDALEETILREGPETVLAFILEPIGGLSTGAVVSS
AAYFRRVREICDRHGVLVIFDEIMSGAGRTGAFLAAHHWEGARPDLVTLAKGLAAGYTPL
GCLLAPNRMVDAIANAGGFVHGHTYFTNPLSCAVARAVVDEVVQQDLVARARDMGELLMA
RLSHIASRSPIVGDVRGKGLLTAIEIVADKATRRQLPVAFNAPARLTEHGLKHGIALYNR
RANLGAFGDFQMITPPLTITGAQIDELAGLLEKALADLADEIARKGLAR