Protein Info for ABID97_RS25985 in Variovorax sp. OAS795

Annotation: CaiB/BaiF CoA-transferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 PF02515: CoA_transf_3" amino acids 22 to 389 (368 residues), 365.7 bits, see alignment E=1.5e-113

Best Hits

Swiss-Prot: 43% identical to SCCT_CHLAA: Succinyl-CoA--D-citramalate CoA-transferase (Caur_2266) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)

KEGG orthology group: None (inferred from 66% identity to bbr:BB0461)

MetaCyc: 32% identical to acetyl-CoA:oxalate CoA-transferase (Escherichia coli K-12 substr. MG1655)
RXN0-7075 [EC: 2.8.3.19]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.16 or 2.8.3.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>ABID97_RS25985 CaiB/BaiF CoA-transferase family protein (Variovorax sp. OAS795)
MSNSANQSGQTSSVRDEHTGAMQGLRVLDIATFVAAPFCGTILADLGAEVIKVEQPNGGD
SLRKFGTITECGDSLVWLSEARNKKAVTLDLRKPEGVALFKQLVEKSDVVLENFRPGTLE
KWGIGFEDLRKLNPKLVMLRISAYGQTGPKRGEPGFARIAHAFAGLSWLAGEADGPPVVP
GSTSMADYISGMWGAIGVMAALRNSEITGRGQFIDIGLYESVFRLLDEVAPAFAKYGIVR
ERMGADTVNVVPHSHYQTASGEWVALACTNDKMFERLAVVMDKPELANTYPTSVVRVENR
ALVNSLVAEWMATYTLSEVLERTRDGGVPCAQIYSIKDIFEDEQYRARGNLLHVYDPRAG
ELVLPAPMPLLSETPPQFRHAGRALGADNAEIFGELLGLSEKQRSDATAAGVI