Protein Info for ABID97_RS24760 in Variovorax sp. OAS795

Annotation: sugar ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00005: ABC_tran" amino acids 31 to 181 (151 residues), 105.7 bits, see alignment E=3.3e-34 amino acids 280 to 444 (165 residues), 75 bits, see alignment E=1e-24

Best Hits

Swiss-Prot: 46% identical to RBSA2_RUBXD: Ribose import ATP-binding protein RbsA 2 (rbsA2) from Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)

KEGG orthology group: K10441, ribose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 92% identity to vap:Vapar_4637)

MetaCyc: 36% identical to galactofuranose ABC transporter putative ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-491 [EC: 7.5.2.9]; 7.5.2.9 [EC: 7.5.2.9]

Predicted SEED Role

"Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (543 amino acids)

>ABID97_RS24760 sugar ABC transporter ATP-binding protein (Variovorax sp. OAS795)
MNAPAAALNASLAAPVLALDALGKDYAAPVLDDVSLMLNAGEVLALTGENGAGKSTLSKI
VCGLVQPTRGQMVLGGAPFQPASRRDAERLGVRMVMQELGLVTTLSVAENLLLDRLPNQA
GWIRRGTLHELAARQLAKIGMQNIDPATPVARLGIGQQQMVEIARNLQDDTRVLVLDEPT
AMLTPRETSHLFEQIELLKARGVAIVYVSHRLEELQRIADRVAVLRDGRLVDVRAMAGVR
ESELVQRMVGRAVHEHEGRGRRVAGPVLLSARGIGRAEVVKDVDIDLHAGEVMGLAGLVG
SGRTELVRLLFGADRADRGEILLHDGTPGSAPVQRARKGWRSPMQAIRAGIGLVTEDRKS
QGLLLTQSIRVNATLSDLGAISRAGWLQRARERGIAKRLVDVLRIRSRSIEQPVATLSGG
NQQKVVFARWLHRECKVLLLDEPTRGVDVGARADLYAELDRMTDAGKALLMVSSDLRELM
AMCDRIGVMSAGRLVAVFERGQWSEQSLLAAAFSDAAGRAANPRAGSAISDPNPAQPATA
ETP