Protein Info for ABID97_RS23940 in Variovorax sp. OAS795

Annotation: cytochrome c oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00510: COX3
  • amino acids 12 to 292 (281 residues), 187.3 bits, E=2.5e-59

Best Hits

KEGG orthology group: K02276, cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 97% identity to vap:Vapar_4387)

Predicted SEED Role

"Cytochrome c oxidase polypeptide III (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

• aerobic respiration I (cytochrome c) (3/4 steps found)
• aerobic respiration II (cytochrome c) (yeast) (3/4 steps found)
• arsenite to oxygen electron transfer (1/2 steps found)
• arsenite to oxygen electron transfer (via azurin) (1/3 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Protein Sequence (293 amino acids)

>ABID97_RS23940 cytochrome c oxidase subunit 3 (Variovorax sp. OAS795)
MSSTTHGTTPYYFVPGPSAYPVMAATGLFFVILGAGQWINGHQWGAWSLLIGMVAWLATL
FVWFRTAIGESESGQYGHKIDLSFRWSMSWFIFSEVMFFGAFFTALWWTRTHSLPALGSL
ENALLWPDFKAVWPSIAAGATGSPADIVEPFQTVGPFWLPTINTALLLSSGVTLTIAHHA
LRADHRAQCIRFMWLTVLLGVIFLGVQGYEYHHLYTELNLKLSSGAYGSTFFMLTGFHGL
HVFIGMLMLLFITLRLQKGHFTPERHFGFEGAAWYWHFVDVVWLGLYMLVYWL