Protein Info for ABID97_RS23930 in Variovorax sp. OAS795

Annotation: SURF1 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 233 to 254 (22 residues), see Phobius details PF02104: SURF1" amino acids 27 to 241 (215 residues), 139 bits, see alignment E=1.4e-44

Best Hits

KEGG orthology group: None (inferred from 92% identity to vap:Vapar_4385)

Predicted SEED Role

"Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (269 amino acids)

>ABID97_RS23930 SURF1 family protein (Variovorax sp. OAS795)
MTPEPLKPTRAASGRGRFLLVTLAAVLTVAATVSLGRWQLSRAAQKEALQAEIESQKQKP
PLAQAEFLSLEAPAGELHRPVRLRGLWLTPQTVYLDNRQMHGVPGFYVLTPFALEGSDQT
VMVQRGWVQRNFNDRTHLGAVDTPPGLVEVTGLIEPPPGHLFELGKPAPAASAPDAAGSS
PIRQNLDLEAFRAETKLPLRTDVSLQQVGPASEGLQRDWPAPALGLEKHYGYAFQWFGLS
ALVVILYVWFQFIAPFRRSRRRARDARSL