Protein Info for ABID97_RS23610 in Variovorax sp. OAS795

Annotation: HlyD family type I secretion periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 27 to 47 (21 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 23 to 445 (423 residues), 319.1 bits, see alignment E=2.5e-99 PF00529: CusB_dom_1" amino acids 215 to 398 (184 residues), 33.3 bits, see alignment E=7.6e-12 PF16576: HlyD_D23" amino acids 244 to 376 (133 residues), 30.8 bits, see alignment E=3.5e-11 PF13437: HlyD_3" amino acids 296 to 404 (109 residues), 48.8 bits, see alignment E=2e-16

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 96% identity to vap:Vapar_5957)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>ABID97_RS23610 HlyD family type I secretion periplasmic adaptor subunit (Variovorax sp. OAS795)
MIHPGHAIAANDPLALHVREARRLTHWGLAVLVCGLFPAAAWLGFAPLSSAVVAQAHVKV
DLNRRPVQHAEGGIVREVLVRDGQHVRQGEPLLVLGDVSVDADRNRLDHRVKTERASLAR
LDAEQTMARAIAFPPDVIETAAADPRLAAQLDKERALFEARRDALVGQVRLLRSQREKVA
EEIVALRAQIMQASESMKFQKSDLETNRKLLKDGFVSAARIAQFEGTVADYGVKIEERRA
ELARAEQRTVDADLRIRSLESEYRQQASDQLKVTAARLAEIEQERRKSADASARQVITAP
ASGEIIDLKYSTPGAVIPPRETIADVVPDDSRLMTDARVRPEDIGRIQRGQAADIRFTAF
KYRTTQLVRGKVVYVSGDRLIDRATNAPYYSVLVEADPPSLATAGDLKLLAGMPAEIYLQ
GEERTALQYLMEPITQVLRRAARER