Protein Info for ABID97_RS23265 in Variovorax sp. OAS795

Annotation: type IV pilus secretin PilQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 718 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF11741: AMIN" amino acids 48 to 129 (82 residues), 37.8 bits, see alignment E=2.6e-13 amino acids 160 to 262 (103 residues), 98.5 bits, see alignment E=3.1e-32 TIGR02515: type IV pilus secretin PilQ" amino acids 274 to 711 (438 residues), 500.1 bits, see alignment E=2.8e-154 PF03958: Secretin_N" amino acids 372 to 449 (78 residues), 50.6 bits, see alignment E=2.7e-17 PF00263: Secretin" amino acids 557 to 711 (155 residues), 157.7 bits, see alignment E=3.3e-50

Best Hits

KEGG orthology group: K02666, type IV pilus assembly protein PilQ (inferred from 94% identity to vap:Vapar_1144)

Predicted SEED Role

"Type IV pilus biogenesis protein PilQ" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (718 amino acids)

>ABID97_RS23265 type IV pilus secretin PilQ (Variovorax sp. OAS795)
MNHKKSTMAQRLRAAGLGLLAFGALAIAHAQNAIEAVTSSTQSGAEVIRIDLAQPLAAVP
TGFAVQTPARIALDFPGVTNAIGRSAIEVNQGNLRSVNVVQAGDRSRVVLNLKQATAYKA
EIQGKSLLVILEPVAGTALASSTPTVFAENRNRDTLPLRDVDFRMGSDNTGRVIVDLPNN
QVGVDVRQQGKNLVVEFTKSTLPEGLRRRLDVADFNTPVQLITSQQSGDRVRMTIEAKGD
WEHSAYQSENQFVVEVRARKVDPAKLTQGVGYNGEKLSLNFQNIEIRSLLQVIADFTNFN
IVTSDSVTGALTLRLKDVPWDQALDIIMQAKNLGMRKNGSVLWIAPKDEINAKEKLEFEA
KATIENLEPVRTQSFQLNYTKAIAIAQGLTGTGASSGGGGGSGTTTRILSPRGSVIAESR
TNQLFVSDIPSRLAQVAELIQKLDIPVRQVLIEARIVEASDTFGKSLGVRLGGGIAGERF
ASSSGNRAFGNIGMMPVVSAGTNATGGASTATTTWTNSNFINLPAGDAGGTGNAAGAFAI
SLFNSSFSRMLNLEISALEADGKGKLVSSPRVITADQTKALIEQGEEIPYQQATSSGATS
ISFRKAVLKLEVTPQITPEGNIILTLDVSKDARGVNTSAGPAINTKHVQTEVLVENGGTV
VIGGIFELTETNDESRVPVLGEVPYLGALFRKRERVANKTEMLVFITPKMITDRNAAR