Protein Info for ABID97_RS22940 in Variovorax sp. OAS795

Annotation: single-stranded-DNA-specific exonuclease RecJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 574 TIGR00644: single-stranded-DNA-specific exonuclease RecJ" amino acids 22 to 568 (547 residues), 429.2 bits, see alignment E=9.3e-133 PF01368: DHH" amino acids 73 to 203 (131 residues), 77 bits, see alignment E=2.4e-25 PF02272: DHHA1" amino acids 320 to 456 (137 residues), 63 bits, see alignment E=6.4e-21 PF17768: RecJ_OB" amino acids 473 to 569 (97 residues), 62.3 bits, see alignment E=6.4e-21

Best Hits

KEGG orthology group: K07462, single-stranded-DNA-specific exonuclease [EC: 3.1.-.-] (inferred from 96% identity to vap:Vapar_1208)

Predicted SEED Role

"Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-)" in subsystem DNA-replication or DNA Repair Base Excision or DNA repair, bacterial RecFOR pathway (EC 3.1.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (574 amino acids)

>ABID97_RS22940 single-stranded-DNA-specific exonuclease RecJ (Variovorax sp. OAS795)
MKIIAREIPPRTVWALEQAGVHPLLARLFAARGVLAKDELDDGLARLLPPDTLHGTREAA
VLLADAMAQHKRLCIVADYDCDGATACAVAVRGLRLLGARNVSYLVPDRVVDGYGLTPPI
AERVADSGADMLITVDNGIASVEGVAAAKARGLQVLVTDHHLPGPELPAADVLVNPNQPG
CGFESKSIAGVGVMFYVLLALRSELRARGTFTPASQPKLDVLLPLVALGTVADVVKLDAN
NRRLVAQGLRRIRAGALPAGIAALFKAAGRNAAVATTFDFGFALGPRINAAGRLADMTLG
IECLLTDDAGRADELARMLDGINRERRDIEGGMRDQALLLAESLFGPTAEGGEAPPAAIS
VFDADFHEGVVGIVASRIKDRFHRPAFVFAASGAPGKAHELKGSGRSIPGFHLRDALDLV
AKRHPGVLLRFGGHAMAAGCTVARDKFEVFEQALAEVAHEWLDAATLTRRLDTDGPLARE
YMRIDLVDTLHREVWGQGFAPPTFSEEVEVVSQRLVGEKHLALKLRHQGQPVDGIWFGHT
DPLPARVTLAFRLDADEWQGVRRVRFLVEGAELP