Protein Info for ABID97_RS22705 in Variovorax sp. OAS795

Annotation: ATPase, T2SS/T4P/T4SS family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 PF05157: MshEN" amino acids 89 to 175 (87 residues), 48.2 bits, see alignment E=8.8e-17 PF00437: T2SSE" amino acids 208 to 591 (384 residues), 407.2 bits, see alignment E=5.1e-126

Best Hits

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 98% identity to vap:Vapar_1249)

Predicted SEED Role

"Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (598 amino acids)

>ABID97_RS22705 ATPase, T2SS/T4P/T4SS family (Variovorax sp. OAS795)
MSAVPAVSAPAPLAARHEGPLDLRRLIEWLATDGVISPVEAKRTIARCAQAQSRQAPLVR
LANVAMTRESDGKPLDLEMLTQWLAVRAGLTYLRIDPLKVDVGKVADTMSAAYAERHKVL
PVQVLPTEVVVATAEPFLTDWIAEVERQSRRTVRRVVANPADIQRYTAEFFALAKSVRAA
QKAGGNTGGASFEQLVELGKSTKQLDANDQSVVQVVDWLWQYAFDQRASDIHLEPRREQG
VIRFRIDGILHPAYQMPMGVMNAMVSRIKLLGRMDVVEKRRPLDGRIKTRNMRGDEVEMR
LSTLPTAFGEKMVMRIFDPDTAVKDLDALGFAQHDAHRWEQLVTRPNGIILVTGPTGSGK
TTTLYSTLKRVATEEVNVSTVEDPIEMIEPSFNQTQVQPQLDFGFTEGLRALMRQDPDII
MVGEIRDLATAEMAVQAALTGHLVFSTLHTNDAPSAITRLMELGVPSYLINAVMLGVLAQ
RLVRTLCPNCKQPDDTVTREKLEAIVKPWQITGSVRAYKPVGCVDCRMTGYMGRMGLYEL
LSISEDFKAQVNKEPNLAGLRRQAVIDGMRPLRLAGALRVAEGVTTIEEVLSATPPLE