Protein Info for ABID97_RS22625 in Variovorax sp. OAS795

Annotation: HAMP domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 37 to 56 (20 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 102 to 120 (19 residues), see Phobius details amino acids 128 to 148 (21 residues), see Phobius details amino acids 156 to 177 (22 residues), see Phobius details amino acids 184 to 202 (19 residues), see Phobius details PF00512: HisKA" amino acids 240 to 303 (64 residues), 42.3 bits, see alignment E=6.2e-15 PF02518: HATPase_c" amino acids 348 to 454 (107 residues), 75.2 bits, see alignment E=5.8e-25

Best Hits

KEGG orthology group: None (inferred from 96% identity to vap:Vapar_4027)

Predicted SEED Role

"FIG00931285: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (470 amino acids)

>ABID97_RS22625 HAMP domain-containing sensor histidine kinase (Variovorax sp. OAS795)
MANASIASTPVPASADEAESWVRGELIRSLMRSARGSYIVSAALMPLMVGLNWSYIPHWE
LLTWLAAGLIATACRAWGAQVYAVRYAGRSAAAQQQFTERYGFIWSTSAVVWGTSVLLFF
ERTPQVNQFMSWLIVAGVGTFPLNGLALHPPLLKRYVNTLFITMLGAVLIRLLSINIVEP
HFQYGFLMPILPILHWFLLLRAGRHIHETARNSLELLFHNHILIKSLTQQRQAAVAAVAM
KNRFLASAAHDMRQPVLALSLYADWLRNEPELVLELAPKIVRATHAVNALFDSMFDLARI
DSGQVRLHIERVDVGELLHDLELQYRPVAESRGLDFRVHVTEGSFLTDPIRVRRMIGNLL
ANAIKYTADGGVLLASRGAGEDLRIEVWDTGIGIAPENLRDVFLEFYKVADHAGTSDGFG
LGLAIVARLSHVLGHPVSVRSRLGSGSVFRVALHDADEAVAQARVSASGG