Protein Info for ABID97_RS22515 in Variovorax sp. OAS795

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 PF00072: Response_reg" amino acids 12 to 123 (112 residues), 91.4 bits, see alignment E=4.2e-30 PF00196: GerE" amino acids 150 to 204 (55 residues), 58.7 bits, see alignment E=3.5e-20

Best Hits

Swiss-Prot: 34% identical to LIAR_BACSU: Transcriptional regulatory protein LiaR (liaR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 95% identity to vap:Vapar_3992)

MetaCyc: 32% identical to DNA-binding transcriptional dual regulator NarL (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (214 amino acids)

>ABID97_RS22515 response regulator transcription factor (Variovorax sp. OAS795)
MANQHAPPIRLFLVDDHPLVRDGLRARLGAMPNLEIVGEAGSAAEALALVDSLQPDLLLM
DVGMKDMNGIDLAALVLQRQPAPHVVMLSMYDNPEYVQKALQVGARGYVLKDAPAAEIVA
AIEAVSGGGTFLSPAVSKKLFRNQAPRPLLTPRESEILSALGRGESSKQIARDLGLSVRT
VEAHRQSIKRRLGIEGQAELIKYAVEHAREFGRE