Protein Info for ABID97_RS22170 in Variovorax sp. OAS795

Annotation: magnesium-translocating P-type ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 907 transmembrane" amino acids 103 to 121 (19 residues), see Phobius details amino acids 127 to 144 (18 residues), see Phobius details amino acids 297 to 317 (21 residues), see Phobius details amino acids 325 to 349 (25 residues), see Phobius details amino acids 715 to 737 (23 residues), see Phobius details amino acids 777 to 800 (24 residues), see Phobius details amino acids 811 to 830 (20 residues), see Phobius details amino acids 842 to 862 (21 residues), see Phobius details amino acids 874 to 896 (23 residues), see Phobius details TIGR01524: magnesium-translocating P-type ATPase" amino acids 47 to 907 (861 residues), 1350.8 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 54 to 119 (66 residues), 54.8 bits, see alignment 1.5e-18 PF00122: E1-E2_ATPase" amino acids 160 to 358 (199 residues), 141.6 bits, see alignment E=5.1e-45 TIGR01494: HAD ATPase, P-type, family IC" amino acids 278 to 416 (139 residues), 70.8 bits, see alignment E=7.9e-24 amino acids 616 to 737 (122 residues), 101.3 bits, see alignment E=4.4e-33 PF00702: Hydrolase" amino acids 374 to 662 (289 residues), 55.9 bits, see alignment E=1.9e-18 PF13246: Cation_ATPase" amino acids 438 to 488 (51 residues), 37.9 bits, see alignment 3.6e-13 PF00689: Cation_ATPase_C" amino acids 731 to 897 (167 residues), 62.2 bits, see alignment E=1.4e-20

Best Hits

Swiss-Prot: 67% identical to ATMA_ECO57: Magnesium-transporting ATPase, P-type 1 (mgtA) from Escherichia coli O157:H7

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 68% identity to adn:Alide_0116)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (907 amino acids)

>ABID97_RS22170 magnesium-translocating P-type ATPase (Variovorax sp. OAS795)
MKNVLKSVFESFLRSRRMLHHFERWQVLLGAKPVGVASAAVPPGIATALAAASHAGAGEL
LASLGSSPQGLEESHAQLLRKRIGSNEVRHEQPLSWWTHLWQCYRNPFNLLLTVLALISY
ATEDMKAALVIGSMVVLSTVLRFLQESRSNSAAERLKAMVSNTATVLRPGAGTQGAVRIE
VPMRDLVPGDVIALSAGDMIPADCRLLATKDLFISQSALTGEAMPVEKFPLDRSGREAGV
LERENLLFMGTNVISGTATALIVHTGERTFFGALAERVTAADSGPSAFQAGINRVSWVLI
RFMLVMAPLVLVINGVAKGDWWEAALFALSIAVGLTPEMLPMIVTATLAKGAVVMSRRKV
IVKRLEAIHNFGAMDVLCTDKTGTLTQDRIVLERHTNAWGEVSDHVLQLAYLNSFHQTGL
KNLLDKAVLDHAELQPGAGQETAWRKFDEVPFDFSRRRMSVVVENRGKEHLLICKGALEE
ILSVCTFVERGAEVLPLDAGLLARIHRVASELNAQGLRVVAVASCTRTAEARKPAYGVAD
ESGLTLLGYVAFLDPPKESTAPALRALAAHGVAVKVLTGDNELVTRKVCGDVGIDAGRIV
LGREIEALGDDELRTLAERHQVFAKLTPAHKERIVRALHANGHVVGFMGDGINDAPALRA
ADIGISVDGAVDVAKESADIILLEKSLMVLEQGVVEGRRTFANMLKYIKLTASSNFGNVF
SVLVASAFLPFLPMLPLHLLVQNLLYDVSQIAIPFDNVDEEFLKSPQQWNPADLGRFMVF
FGPLSSVFDILTYAVMWFAFSANTAAQQTLFQSGWFIEGLLSQTLIVHLIRTRKIPFLQS
RAAWPLLAMGAAIVAAGIWLPMGRLAHYFRLQALPLAYFPWLAAILAGYAALTQAVKGWY
ARRYGWQ