Protein Info for ABID97_RS21725 in Variovorax sp. OAS795

Annotation: aldo/keto reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 PF00248: Aldo_ket_red" amino acids 16 to 310 (295 residues), 210.5 bits, see alignment E=1.5e-66

Best Hits

Swiss-Prot: 39% identical to YAKC_SCHPO: Aldo-keto reductase yakc [NADP(+)] (yakc) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 80% identity to bph:Bphy_3317)

Predicted SEED Role

"Aldo-keto reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>ABID97_RS21725 aldo/keto reductase (Variovorax sp. OAS795)
MNTRQLGATGPRVSALGLGCMGMSALYGPSDRGESIATIHAAMDAGITLLDTGDFYGSGH
NEMLIGEALRGLKGSQRDAALVSVKFGALRDPAGGWSGYDARPEAVKNFLVYSLQRLGVD
YIDIYRPARLDPNVPIEDTVGAIADMVKAGYVRHIGLSEMGSHTIRKAAAVHPIADLQIE
YSLISRGIEDDILATCRELGIGITAYGVLSRGLISGHWKKEGAGATDFRTHSPRFQGENV
DRNLALVDALRKIAEAKGVTVAQIAIAWVAAQGDDIVPLVGARQRNRLREALGSLDVSLG
ADDLAAIERAVPKGAAAGERYAASQMAHLDSEAAGHA