Protein Info for ABID97_RS21700 in Variovorax sp. OAS795

Annotation: glycerol-3-phosphate 1-O-acyltransferase PlsY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase
  • amino acids 8 to 207 (200 residues), 181.8 bits, E=6.3e-58
• PF02660: G3P_acyltransf
  • amino acids 14 to 197 (184 residues), 185.6 bits, E=3.8e-59

Best Hits

Swiss-Prot: 65% identical to PLSY_RHOFT: Glycerol-3-phosphate acyltransferase (plsY) from Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)

KEGG orthology group: K08591, glycerol-3-phosphate acyltransferase PlsY [EC: 2.3.1.15] (inferred from 96% identity to vap:Vapar_3772)

Predicted SEED Role

"Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria

MetaCyc Pathways

• superpathway of phospholipid biosynthesis III (E. coli) (11/12 steps found)
• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (4/12 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.15

Use Curated BLAST to search for 2.3.1.15

Protein Sequence (211 amino acids)

>ABID97_RS21700 glycerol-3-phosphate 1-O-acyltransferase PlsY (Variovorax sp. OAS795)
MSFHLPSLLAIVASYLIGSLSFAVIVSKSLGMADPRSYGSGNPGATNVLRSGKKGAALAT
LLLDALKGWLPVFLIRHFGAQWGLGEGVAGLAGLAAFLGHLYPVFFGFQGGKGVATAAGV
LMGIAPWLGLATGATWLIIAVFFRYSSLAALAAAFFAPAYYLLGGNIAWPLDRTVLIAII
IMSLLLVWRHRENIRRLAAGTESKLGSKKKA