Protein Info for ABID97_RS21480 in Variovorax sp. OAS795

Annotation: amino acid adenylation domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1112 transmembrane" amino acids 295 to 312 (18 residues), see Phobius details PF00668: Condensation" amino acids 48 to 497 (450 residues), 319.7 bits, see alignment E=6e-99 PF00501: AMP-binding" amino acids 518 to 863 (346 residues), 309 bits, see alignment E=8.4e-96 TIGR01733: amino acid adenylation domain" amino acids 538 to 938 (401 residues), 459.8 bits, see alignment E=3.9e-142 PF13193: AMP-binding_C" amino acids 923 to 996 (74 residues), 39.8 bits, see alignment 1.5e-13 PF00550: PP-binding" amino acids 1023 to 1086 (64 residues), 52.7 bits, see alignment 8.5e-18

Best Hits

KEGG orthology group: None (inferred from 77% identity to vap:Vapar_3744)

Predicted SEED Role

"Non-ribosomal peptide synthetase modules, pyoverdine" in subsystem Siderophore Pyoverdine

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1112 amino acids)

>ABID97_RS21480 amino acid adenylation domain-containing protein (Variovorax sp. OAS795)
MSETSLLPERRARLSPAQLSLLQRRLQQGGDAPATRDAIVRGHVDGPAPVSFAQQGQWFL
WQMNPSNTAYHVGGGLGFSGPLDAAALQEAMQSLVRRHAALRTVFGPGPDGLPEQRVLAE
VRIDIPFVDLSVLDPEARELRHGEVVDQACRAPFDLAAGPLLRCALLKMAAGEHQLLLMM
HHIVSDAWSVELMLDELAAAYTLRMQGEEGEQDGKAAPEISHVDYALWQRKWLADGEGDR
QLAYWRKRLGGSQPVLSLTTDRPRSPEPCYSAAQHSLHVPAALAQQLRQLSRARGGTLFM
ALLAAFHALLFRHTGQEEIRIGVPVAGRGRPETAGVVGIFINTLVLDARLDAQTALGDLL
AQVRDTAIEAQAHQDLPFERVVQALRADHGHAAAPLFQVMFNHLGQGDRPLRGWPGLNVR
RIDLAQRAAPFELTLETIEREDGGIQANFRYAAELFEPQTLERMAGHYLRVLEALAGRPA
SRLGELDMLGDAEQAMLAQWGVNAHRRGEAQCVHRLIEQQTAECPDAAALLFGTETVSYG
ELNRRANRLAYRLIEAGVRPEVKVGVALDRSAELVVSLLAILKAGGAYVPLDPGYPADRI
AYMVQDSGLALVLTQACLQERLPLHFGVPMLALDTLDLGDHPDSNPAVAIDGENLAYVIY
TSGSTGKPKGAANRHGSLYNRLVWMQQALRLGEADTVLQKTPFSFDVSVWEFFWPLMFGA
RLAVAEPGDHREPARLVHLIRAHAVTTLHFVPSMLQAFLAHPGIEACGSLRRIVCSGEAL
PAEAQNEVFRRLPQTTLHNLYGPTEAAIDVTHWTCRDDGRTQVPIGRPIDDTQVHVLDAG
LNLVPSGAAGELYLGGAGLARGYVRRAALTAERFVADPFGGEGARLYRTGDLVRWNSEGQ
LDYLGRIDHQVKIRGFRIELGDIEAQLLAQPEVREAVVVASQGVGGARLVAYVSAQAGQA
IDTVRLREQLGRVLPDYMVPGLFMVLETLPLNANGKVDRKALPEPERATAQACEAPQGAG
EVALAAIWAEVLGVPRVGRHDNFFELGGHSLMAVQVVARVQAAMHADLTVADVFRQPVLM
DMARLIADAAERKPVAQSLSDIEAFMDSLEIA