Protein Info for ABID97_RS19530 in Variovorax sp. OAS795

Annotation: haloacid dehalogenase-like hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Best Hits

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_3280)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• superpathway of L-serine and glycine biosynthesis I (4/4 steps found)
• L-serine biosynthesis I (3/3 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.3

Use Curated BLAST to search for 3.1.3.3

Protein Sequence (422 amino acids)

>ABID97_RS19530 haloacid dehalogenase-like hydrolase (Variovorax sp. OAS795)
MQRRLLLLTPLAAALTATGCASLAPSASTTLSPGHWDAFNRAQIEGLVASLGKASPGYSA
AKPPYVVFDWDNTSVFLDIEEASLIYQLENLVFGATPAQLEVALRKNIPKKDFLPAYNNA
AGKAVNIDLLVPDIVASYTWLYQNYSGLKGSQPLAAVKLNPHYIAFTTKVRYLYEAIGDT
FDHDTAYPWVTYLFVGMTEPQVRKLTAETVAWQLKEPVAKVKWTSPAALPGQAGVVSVSW
KNGLRLQPEMQELYAVFRNAGFDVWVCSASFVDVIKEISSNPAFGYDNPAERVLAMELER
DANGVIQPEYRRGYDQTQGPGKTRNIQRFLVSKYGYGPSFIAGDSEGDQNMMADFADTKK
VLIVNRLRDPKTDIGRFSAMAVQNYGKPDTRYLLQGRDDNLGQWVTSQLHTPLGAAQGKA
LK