Protein Info for ABID97_RS19465 in Variovorax sp. OAS795

Annotation: CoA transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 4 to 372 (369 residues), 421.7 bits, E=1.4e-130

Best Hits

Swiss-Prot: 49% identical to SCCT_CHLAA: Succinyl-CoA--D-citramalate CoA-transferase (Caur_2266) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_3268)

MetaCyc: 35% identical to acetyl-CoA:oxalate CoA-transferase (Escherichia coli K-12 substr. MG1655)
RXN0-7075 [EC: 2.8.3.19]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

• oxalate degradation II (2/3 steps found)

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.16 or 2.8.3.19

Protein Sequence (391 amino acids)

>ABID97_RS19465 CoA transferase (Variovorax sp. OAS795)
MNALEGLKVLELGQLIAGPFAGKTLAEFGADVIKVEPAGVGDPLRKWRLLREGTSVWWEV
QSRNKRSVCLDLRSPEGQEAVRTLALEADVLIENFKPGTLEGWGLGWERLHALNPRLIML
RISGYGQTGPYRDKPGFGVLGESMGGLRHLSGEPGRVPVRVGVSLGDTLAALHGVIGVLT
ALHHRTAHGGEGQFIDVALYESVFNVMESLLPEYDAFGVVRERAGSALPGIAPSNAYKCL
DGHHVLVAGNGDSIFRRLMRAIERTDLENDPGLVHNDGRVRRVEEIDAAIEAWTLQRSRD
EVLAVLDAAGVPVGRIYSVADIAADPQYLARQMIVETTTADGEMLKVPGVVPKLSATPGR
IARPAPRLGEHTGDLQDAGWPARRTEESEAV