Protein Info for ABID97_RS19120 in Variovorax sp. OAS795

Annotation: polysaccharide biosynthesis tyrosine autokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 762 transmembrane" amino acids 39 to 56 (18 residues), see Phobius details amino acids 450 to 471 (22 residues), see Phobius details TIGR01005: exopolysaccharide transport protein family" amino acids 25 to 745 (721 residues), 417.6 bits, see alignment E=9.4e-129 PF02706: Wzz" amino acids 25 to 113 (89 residues), 45.9 bits, see alignment E=1.8e-15 PF13807: GNVR" amino acids 394 to 473 (80 residues), 95.9 bits, see alignment E=3.3e-31 TIGR01007: capsular exopolysaccharide family" amino acids 533 to 731 (199 residues), 147.6 bits, see alignment E=3.6e-47 PF10609: ParA" amino acids 550 to 719 (170 residues), 33.9 bits, see alignment E=6.8e-12 PF13614: AAA_31" amino acids 552 to 673 (122 residues), 49.4 bits, see alignment E=1.7e-16 PF01656: CbiA" amino acids 552 to 724 (173 residues), 34.9 bits, see alignment E=4.3e-12

Best Hits

Swiss-Prot: 45% identical to EPSB_RALSO: Putative tyrosine-protein kinase EpsB (epsB) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: None (inferred from 81% identity to vap:Vapar_3190)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (762 amino acids)

>ABID97_RS19120 polysaccharide biosynthesis tyrosine autokinase (Variovorax sp. OAS795)
MNAHWQPMIPAPSETMAADRPPSRLREHFDLLLDHRWKIAKITAVALLIGAAYTMFGPRV
YESNVLIQVEDSERSGGTLVGDSASSALNAKTPTAGEAEILKSRLVLEQAIEDTKLYIEA
QPHYIPVVGAWLARHSKTLSDPGFAGLSGYVSGTEQIVVAQMDVPPELEGTRFLLTAKAD
GAYTLTHPKLDATLEGKVGTPLDAKTPRGPIHLLVGSIAGRPGAAFELVRQSKQLTLLEL
QKDLRVIEKGKQSSIMDVSWRDGNPLQLANLLNEVARLYVRTNIDQKTEQAQRALNFLGT
ELPKLKLQLEQSEETYNQYRNQNGTISLDDEARNALSQNVELQAKLLDATQKRLELTERF
TARDPSVQTIDAQIASLKKGLGSVEQRIRRMPLLQQNSLRMQRDIKVNTDLYVSLLNSSL
QMRLAKEGKIGNVRVLDQAVVPEKPIRPKAAITMVLALLAGLFAGAASAFMRRSWRNTIA
SSAEIEAYTGLTVYSTVPLSPQQRLLDRAVQQGKPGVHLLAALHPDDQALEGLRRLRTAL
KFAIPNAPNNRIMISSATPGAGKTFVSSNLAAVLASSGRRVLLIDADLRRSSLAPHFGLK
RRGGLSELIQGSVEVDTAIHHSVLPNLDVITTGALPSDPTALLTSEAFAKLLERLSGRYD
TVIVDTPPTLLASETAEMATFMGTLLMVARAGENELGDLSESAKLLRHAGAHFQGVVLNA
LDTRRRYYGGLAYRYGGYRLRMHDYPGAPAELPAPAHAGARS