Protein Info for ABID97_RS18730 in Variovorax sp. OAS795

Annotation: cytochrome P450

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 PF00067: p450" amino acids 105 to 282 (178 residues), 29.6 bits, see alignment E=1.7e-11 amino acids 295 to 388 (94 residues), 67.8 bits, see alignment E=4.2e-23

Best Hits

Predicted SEED Role

"putative cytochrome P450 hydroxylase" in subsystem Nitric oxide synthase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>ABID97_RS18730 cytochrome P450 (Variovorax sp. OAS795)
MRPLSQDASAPRTGPTTRASALFDPFSTAYQNDPHQVLGEIRETEPIFFSPALGSWVVTR
HETVKSILRDTVHFSSKIVSDPLVPLCPHARSIISESSYDVPPMLVNNDPPTHARYRRFF
TEPLKRPRMLALEPFVRKTVNEKLDALLAAPGPADLVSGLTFETPALVLFRALGIPEEDV
PSVKRWADSRMVLQWGKPTEDEQVRIAKGTVDFYSYTEALVRRKLDAPGDDVVSDLLAQR
AGSDENMTLREITGTVFNLLFAGHETTTTAATGMFNNLLRNRPMWESIVAGQQDLDAVVE
ESLRYSPPIIGWRRLVKANVEVLGQPLVVGDRVLMMFGSANRDPEVFEEPESFSPGRSNI
AQHVSFGMGIHYCAGAPLARLELSVMLDIVSKRLPGLRIVDAHALEYVPNTVAHALKKLL
VTW