Protein Info for ABID97_RS17605 in Variovorax sp. OAS795

Annotation: trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 PF05697: Trigger_N" amino acids 1 to 142 (142 residues), 142.3 bits, see alignment E=2.1e-45 TIGR00115: trigger factor" amino acids 11 to 417 (407 residues), 439.1 bits, see alignment E=7.6e-136 PF00254: FKBP_C" amino acids 160 to 238 (79 residues), 61.6 bits, see alignment E=1.1e-20 PF05698: Trigger_C" amino acids 264 to 417 (154 residues), 123.3 bits, see alignment E=1.6e-39

Best Hits

Swiss-Prot: 97% identical to TIG_VARPS: Trigger factor (tig) from Variovorax paradoxus (strain S110)

KEGG orthology group: K03545, trigger factor (inferred from 96% identity to vpe:Varpa_3423)

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>ABID97_RS17605 trigger factor (Variovorax sp. OAS795)
MTVTVETLEKLERKITLTLPVGTIQSEVDSRLKKLARTVKMDGFRPGKVPMNVVAQRYGY
SVHYEVMNDKVGEAFSQAANEAKLRVAGQPRITEKEESPEGQLAFDAVFEVFPEVKINDL
AGAEVEKLSAEVGDDAIDKTLDILRRQRRTFAQRAQDAVVQDDDRVTVDFEGKIDGEPFQ
GGKAEDFQFIVGEGQMLKEFEDAVRGMKSGDSRTFPLSFPADYHGKDVAGKQADFMVTVK
KIEASHLPEVNEQLAKSLGIPDATVEGLRADIKKNLEREVKFRLLARNKNAVMDTLLANA
ELDLPNASVQSEVNRMVEGARAELKQRGIKDADKAPIPDEVFRPQAERRVRLGLVVAELV
RANNLQAKPEQIKAHIDELAASYEKPADVVRWYFSDNNRLAEVEAVVIENNVTEFVLGKA
KVNEKSVTFDELMAQQQG