Protein Info for ABID97_RS17380 in Variovorax sp. OAS795

Annotation: CidA/LrgA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 117 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 25 to 45 (21 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 83 to 106 (24 residues), see Phobius details PF03788: LrgA" amino acids 12 to 104 (93 residues), 88.1 bits, see alignment E=1.6e-29

Best Hits

KEGG orthology group: None (inferred from 91% identity to vap:Vapar_2557)

Predicted SEED Role

"Antiholin-like protein LrgA" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (117 amino acids)

>ABID97_RS17380 CidA/LrgA family protein (Variovorax sp. OAS795)
MLYAITALFLCQLAGELLVQWLGLPVPGPLIGMLLLFVALLARGRVPEALGETAGHLLRN
LMLLFIPAVTGVMLHFERVGREWLPFLAAGIVGAAFTMTVTALTFRWMIRFTGKDAE