Protein Info for ABID97_RS16285 in Variovorax sp. OAS795

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1164 transmembrane" amino acids 22 to 45 (24 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details PF05227: CHASE3" amino acids 46 to 179 (134 residues), 120.2 bits, see alignment E=1.9e-38 PF13185: GAF_2" amino acids 252 to 387 (136 residues), 51.8 bits, see alignment E=3.1e-17 PF01590: GAF" amino acids 259 to 387 (129 residues), 24 bits, see alignment E=1.5e-08 PF00512: HisKA" amino acids 487 to 554 (68 residues), 65.8 bits, see alignment 8.7e-22 PF02518: HATPase_c" amino acids 602 to 711 (110 residues), 100.3 bits, see alignment E=2.7e-32 PF00072: Response_reg" amino acids 773 to 881 (109 residues), 62.3 bits, see alignment E=1.4e-20 amino acids 896 to 1006 (111 residues), 60.5 bits, see alignment E=5.1e-20 amino acids 1042 to 1154 (113 residues), 98.7 bits, see alignment E=6.8e-32

Best Hits

KEGG orthology group: K00936, [EC: 2.7.3.-] (inferred from 62% identity to pfo:Pfl01_2646)

Predicted SEED Role

"Signal transduction histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1164 amino acids)

>ABID97_RS16285 response regulator (Variovorax sp. OAS795)
MKTPTAIDPDDFERLLSRNLKWPLLGGLVGALVFVALIVFLLSAISRVESTDRVVRTATE
LQRRTIDMETGLRGFLITGEESFLEPYQSALPRIKGDIESLRGQVSDNRQQGERVGRIAA
LQAEWNEFAREMIAARRSGGDYQQLVRQGRGKRLTDDMRAEFTAFMDTEQGLRFQRNEEA
NRTSWMVVGVFMLFTLVFTGLVAYFGRRQLMRLSASYDAVLQEQAGHAERLAQQAWLRSA
QTELVGELVGELSANDLGRKVLAFFSRRLGSAVGALYVRERHGTLRRAASYGFSMEAEAT
PQVFSPTQSLVGQAAAERRRMLVEPIQADYLKVNSGLGEMAPSAVLLVPVSSDGLVNGVV
ELGLPGPPDARTNELLDLVAEDIGASLAAARYREQLQDALAETQQLNEELQVQQEELRTA
NEELEEQSRALRASQAMLENQQAELEQTNSQLSERTEALDQRNAALRRVQRDLEDRADEL
QRASRYKSEFLANMSHELRTPLNSALILAKLLGDNPQGNLSPEQVKFAESIYSSGNDLLV
LINDILDISKVEAGKLEVVIEDVALDRLAQSLERTFGPLAAEKRLGFKLTMHPDVPASLA
TDRHRVEQILKNLLSNALKFTDSGEVALVVSAAPEGGAVFAVSDSGIGIAPEQQGLIFEA
FHQADGTTSRRYGGTGLGLSISRDLTRLLGGTLSVQSQPGQGSTFTLQLPAVAPQASERG
PAPVPKPAAASAARAPSPFTSSVSHGHGAAPVAAPPPQFSDDRALPRDQVRRVLVIEDEP
QFAHILYDLAHELGYRCLVAHGAADGFELAQQFLPDAILLDMRLPDSTGLDVLQRLKDSP
RTRHIPIHVVSAADNAQAAALHMGAIGYAQKPATREELMQVFARLEDKLTQKVKTVLLVE
DDALQRESVIRLIGDEDIEIIAVGSGEEALELLRKRVFDCMITDLHLPDMQGGELLKRMA
AEEIVSFPPVIVYTGRNLTRDEEAELQRYSRSIIIKGARSPERLLDEVTLFLHKVEAELS
SERQGMLKAARGRDRIFEGRTILLVDDDVRNIFALTSALEQRGAVVEIGRNGREALEKLG
QVPEIDLVLMDVMMPEMDGLEATRRLRADPRFEKLPVIAITAKAMKDDREQCLAAGASDY
LAKPVDLERLFSLLRVWMPKMERL