Protein Info for ABID97_RS16280 in Variovorax sp. OAS795

Annotation: ATP-dependent DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 780 PF06733: DEAD_2" amino acids 281 to 400 (120 residues), 45.4 bits, see alignment E=1.1e-15 PF13307: Helicase_C_2" amino acids 600 to 760 (161 residues), 123.3 bits, see alignment E=1.7e-39

Best Hits

KEGG orthology group: None (inferred from 87% identity to vap:Vapar_2806)

Predicted SEED Role

"DinG family ATP-dependent helicase CPE1197" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (780 amino acids)

>ABID97_RS16280 ATP-dependent DNA helicase (Variovorax sp. OAS795)
MTTDLSTKPQVVPPDDARTVSVKALCAFGAKAGDLDLRFVPAPSALEGMAGHALVQGRRG
ESYQSEVALVSHCGALRVRGRADGYDPRAPRVEEIKTFRGDFDAIRGNHRALHWAQARTY
GWMLCELHGHERITVALVYLDLATGEETVLEEEHDRTALQAHFERLCARYSDWAQSEAAH
QALLGSALGALAFPHGKFRAGQRELAEAVYRAAVNGRCLMAQAPTGIGKTLATLFPLLKA
RAARKIDRIFFLTAKTSGRAVALDALRVLGKGAPVRVLELTARDKVCEYPDRACNGDSCP
LAKGFYDRLPAAREDAARAPRLDRQSLRHIALAHTVCPYFLAQEMAHWCDVIVGDYNYYF
DGSAFLYATMKDADWRAAVLVDEAHNLLERARGMYTAQLDGPALEEAHRAAPATVRGALG
RLYREWDTVQQSQTESYDTADEIPERFARALQAANTAMGEYFAATPDAAQGPLQRFFFDA
LQFARLAEAFDDHSVFERTLGPAQDQQQRSLAIRNLVPAPFLEPRFAEASSVTCFSGTLS
PFGFYRDALGLPPETLLLDVASPFHGHQLRVEVATHVSTRFRDRAGSLRSVAEIIGAQFE
RLPGNYLAFFSSFDYLEKACAAFLARHPGVPVWAQTRGMAEAERHDFVARFEVGGRGIGF
AVLGGAFGEGIDLPGSRLVGAFVASLGLPQYNALNEITRERMQARFGKGYEYTYLYPGLQ
KVVQAAGRVIRTEQDRGVLHLLDDRFARAEIRELLPPWWELRLGGAQAAGKKGESADAVR