Protein Info for ABID97_RS16265 in Variovorax sp. OAS795

Annotation: adenosylmethionine--8-amino-7-oxononanoate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 TIGR00508: adenosylmethionine-8-amino-7-oxononanoate transaminase" amino acids 27 to 445 (419 residues), 512.4 bits, see alignment E=3.8e-158 PF00202: Aminotran_3" amino acids 42 to 441 (400 residues), 317.2 bits, see alignment E=6.9e-99

Best Hits

KEGG orthology group: K00833, adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC: 2.6.1.62] (inferred from 92% identity to vap:Vapar_2810)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (464 amino acids)

>ABID97_RS16265 adenosylmethionine--8-amino-7-oxononanoate transaminase (Variovorax sp. OAS795)
MPPTNASSPMPPASKNAAWQQRSRRHVWHPCTQSIRLEAVPPLPMARGEGVWLYDHDGHR
YMDATSSWWVNLFGHAHPAINAALKDQLDKLAHVMLAGCTHAPAVELAERLAALTGHALG
HCFYASDGASAVEIALKMSFHAWRNAGRSGKQAFVAVRRGYHGETLGALHVTDVPVFRDA
YAPLLANAHLVASPDARTARPGEDALAVARRAAAELEALLAERHASIAAVIVEPLVQCAT
GMAMHDPEYLRLVRALCDRYEVHLIADEIAVGCGRTGTFFACEQAGIWPDFLCLSKGISG
GYLPLALVMTRDAIYEGFVDDDVARSFLHSHSYTGNALACRAAIATLDLFEQEDALHRNR
ARAERLMGRLREGLPGMPVDHLRQRGMITAFDVREPGVRFAERFHMAARANGLLMRPIGA
TVYLMPPYAIGDGEIDLLVDATLATLQAVAASSQAEGGRDVALA