Protein Info for ABID97_RS16070 in Variovorax sp. OAS795

Annotation: dienelactone hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01738: DLH
  • amino acids 15 to 229 (215 residues), 175.9 bits, E=8.9e-56
• PF12680: SnoaL_2
  • amino acids 247 to 354 (108 residues), 29.8 bits, E=8e-11

Best Hits

KEGG orthology group: K01061, carboxymethylenebutenolidase [EC: 3.1.1.45] (inferred from 93% identity to vap:Vapar_5380)

Predicted SEED Role

"Dienelactone hydrolase family"

MetaCyc Pathways

• 4-chlorocatechol degradation (3/5 steps found)
• 4,5-dichlorocatechol degradation (4/7 steps found)
• 3,4,6-trichlorocatechol degradation (5/9 steps found)
• 3-chlorocatechol degradation I (ortho) (2/5 steps found)
• 3-chlorocatechol degradation II (ortho) (2/5 steps found)
• 3,5-dichlorocatechol degradation (4/8 steps found)
• 1,4-dichlorobenzene degradation (4/9 steps found)

KEGG Metabolic Maps

• 1,4-Dichlorobenzene degradation
• Fluorobenzoate degradation
• gamma-Hexachlorocyclohexane degradation

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.45

Use Curated BLAST to search for 3.1.1.45

Protein Sequence (419 amino acids)

>ABID97_RS16070 dienelactone hydrolase family protein (Variovorax sp. OAS795)
MSPYIDIPAADGQAFRGYLALPPSGRGPGIVLCQEIFGINDYVREVADLYAAEGYVVLAP
DLFWRMEPNVELGYSPEDWQRAFGFFQKFDLAAGVADVTASVQALRAHPACTGKVGALGF
CLGGKLAYLAAAHSGVDAAVGYYGVGIEADLDLVPKIGCPIALHFAELDKFCPAEARAQV
LAAFAGKPGAQMYVYPGVDHAFARTGGDHFDKPSTLMAHQRSMALFKEAIGPVYDLSALW
DKHCEYEFATRDVAATMGTMVAEPYVNHIPTMTGGVGARELSRFYKHHFIPTTPPDTRLT
PISRTVGATQIVDEMLFSFTHTVEIDWLLPGIAPTGKAVEIPLVAIVKFRGDKLYHEHIY
WDQASVLVQIGLLDPKGLPVAGVETARKLVDENLPSNTLMPRWPKSAALTMADPALPLG