Protein Info for ABID97_RS15665 in Variovorax sp. OAS795

Annotation: [protein-PII] uridylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 868 TIGR01693: protein-P-II uridylyltransferase" amino acids 35 to 866 (832 residues), 771.9 bits, see alignment E=4.5e-236 PF01909: NTP_transf_2" amino acids 65 to 99 (35 residues), 22.9 bits, see alignment (E = 2.3e-08) PF08335: GlnD_UR_UTase" amino acids 171 to 310 (140 residues), 137 bits, see alignment E=1.1e-43 PF01966: HD" amino acids 472 to 540 (69 residues), 30 bits, see alignment E=1.4e-10

Best Hits

Swiss-Prot: 62% identical to GLND_CUPNJ: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 96% identity to vap:Vapar_2942)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (868 amino acids)

>ABID97_RS15665 [protein-PII] uridylyltransferase (Variovorax sp. OAS795)
MIEPAKIDVATLREAYRAKKLALFDTLRFARAPTRSVHTVLRQLSALADQTLCALWQEAD
FGDALSLAAVGGYGRGELFPYSDVDVLLLLPPEGHASEIDPARIEAFIGHCWDAGLEIGS
SVRTVEECLAEAEKDVTVQTSLLESRLVAGDKKLFVAFRRRFARAIDPQAFFVAKSQEMR
HRHQKYDSTPYALEPNCKESPGGLRDLQTILWMTKAAGFGNRWDDLAKNGLATSFEAQQI
KRNEALLSLIRARLHVIAKRREDRLVFDLQTAVAASFGYESESQRKSSEALMRRYYWAAK
AVSQLNQILLLNIAERLQPVDEQHTPINERFYERSGLIEIASDDLYEREPHAILETFLLY
QKTIGVQGLSARTLRALYNARHVMDSKFRNDPVNHETFMRIMLQPYGITHAFRLMNQTSV
LGRYLRVFRSIVGQMQHDLFHVYTVDQHILMVLRNVRRFFIAEHAHEYPFCSQLAAGWDK
PWILYVAALFHDIAKGRGGDHSTLGARDVQRFCKQHGIAREDAKLIEFLVAEHLVMSQVA
QKQDLSDPEVIGAFARRVGNERYLTALYLLTVADIRGTSPRVWNAWKGKLLEDLYRYTLR
ALGGRMPDPDAEVESRKREALVQLALHAQRFEAHKALWDTLDVGYFMRHDATEIAWHAKQ
LSRFVPPPNVPVDPKAPPVVRAHLSPVGEGLQVVVYTPDQPDLFARICGYFDQSSFSILD
AKVHTASNGYALDTFQVVTTFQPDHYRDLISMVESGLAQTLTEAGPLPAPSVGRVSRRVR
SFPIKPRISLLPDDKAQRWLLNISASDRAGLLYSVARVLARHHLNLQLAKVTTLGERVED
TFLISGPELQGQKTQLAIETDLMEALAS