Protein Info for ABID97_RS15615 in Variovorax sp. OAS795

Annotation: chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1171 TIGR02168: chromosome segregation protein SMC" amino acids 2 to 1161 (1160 residues), 1056.2 bits, see alignment E=0 PF02463: SMC_N" amino acids 3 to 1154 (1152 residues), 216.2 bits, see alignment E=7.9e-68 PF13476: AAA_23" amino acids 5 to 222 (218 residues), 37.3 bits, see alignment E=9.2e-13 PF06470: SMC_hinge" amino acids 524 to 622 (99 residues), 28 bits, see alignment E=5e-10

Best Hits

Swiss-Prot: 75% identical to SMC_DELAS: Chromosome partition protein Smc (smc) from Delftia acidovorans (strain DSM 14801 / SPH-1)

KEGG orthology group: K03529, chromosome segregation protein (inferred from 77% identity to adk:Alide2_2444)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1171 amino acids)

>ABID97_RS15615 chromosome segregation protein SMC (Variovorax sp. OAS795)
MRLNSIKLSGFKSFAEPTNFLLPGQLVGVVGPNGCGKSNIMDAVRWVLGESRASELRGES
MQDVIFNGTTTRKQASRSSVELVFDNADHRAGGQWNQFGEIAVRRVLTRDGTSSYYINNQ
PVRRRDVQDVFLGTGLGPRAYAIIGQGTISRIIESKPEELRLFLEEAAGVSKYKERRRET
ESRLGDTRENLTRVEDILRELNANLEKLEKQAEVAARYNTLQGEASKKQHQLWFLKRSES
DADQAKIKAESEKAINDLESRTADLRRIEAELETVRQAHYAAGDQVNQAQGKLYEASAEV
GRLEGEIRFVVEGRQRVEQRLVQLREQMGQWGRRREEAEAEIETLAGQGVDAEEQAVLLA
AQLEEHDARMPELEEAVQRAQDVANSQRAAVGQIQQQIQVLAADQRNIEDQSRQLTQRSE
RLRADQNALAAPDEARLQAMQEEHAAAQEAAGEADARLHELQESVPQLDDDRRVKQQAVN
TESARHAELSARLEALRALQEKVKTDGKLAPWLARHGLEGMQGLWSRIHIEQGWENALEA
ALRERLGALEVSRLDMVRAFGNDAPPAKLAFYSPPDAGVSQDSGTLPRLSGLLRLNDAGL
QALMTDWLHGCYIAQSFEEALAERATLKPGEVIYVQSGHAVFSHSVNFYAPDSEQAGLLA
RQQEMENLERQLRAQTLISEEARTALIRAEAAYSEAAQRLVAARREAAETQSRAHELQVE
TLRMTQLAEQTRARSEQLAADLAEVDAQLEELQEKRMAAEGRFEELDMQLADSQERHAEL
DERVIEAGRALTASREQHRSLERQAQEATFSQRTLEARRGELNRAIETASQQVVALTDED
ERARAELGRLSDAAAQAGLQDALALKLEREAALGAARSQYDDLTMKLRASDERRLQLERE
LDPLRQRITEFQLKEQAARLGVEQYQQLLDDAGADLEAIAQSIETDKVRLAGLQGEIDRL
NREVVALGAVNLAALDELAVASERKTFLDAQSADLNEAIGTLEDAIRKIDGETRELLGGT
FKIVNEHFSRMFPELFGGGNARLVMTGDEILDAGVQVLAQPPGKKNQTIHLLSGGEKALT
AIALVFAIFQLNPAPFCLLDEVDAPLDDANTERYAKLVTAMSRETQFLFISHNKIAMEMA
EQLIGVTMQEQGVSRIVAVDMESAASMVEAA