Protein Info for ABID97_RS15590 in Variovorax sp. OAS795

Annotation: disulfide bond formation protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 168 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 141 to 161 (21 residues), see Phobius details PF02600: DsbB" amino acids 10 to 158 (149 residues), 155.8 bits, see alignment E=5.7e-50

Best Hits

Swiss-Prot: 63% identical to DSBB_ACIAC: Disulfide bond formation protein B (dsbB) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K03611, disulfide bond formation protein DsbB (inferred from 90% identity to vap:Vapar_2957)

Predicted SEED Role

"Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (168 amino acids)

>ABID97_RS15590 disulfide bond formation protein B (Variovorax sp. OAS795)
MIDWFFGAPRRAYGLICLACVLMLAFGLYLQHVVGLEPCPMCIVQRYALVLVALFTGLAG
VFRGRGLQSTGGGLALLAAIGGAYTAASQSWLQWNPPEVVSCGRDLYGMIETFPLKRALP
MIFRGGGDCSKVDWSLFGLTLANWSFVAFAVLAVLLLVLLLRKRPAAR