Protein Info for ABID97_RS15465 in Variovorax sp. OAS795

Annotation: sulfate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR00971: sulfate ABC transporter, sulfate-binding protein" amino acids 35 to 339 (305 residues), 471.4 bits, see alignment E=6.7e-146 PF01547: SBP_bac_1" amino acids 53 to 284 (232 residues), 50.4 bits, see alignment E=4.9e-17 PF13531: SBP_bac_11" amino acids 55 to 293 (239 residues), 130.6 bits, see alignment E=1.2e-41 PF13343: SBP_bac_6" amino acids 127 to 306 (180 residues), 28 bits, see alignment E=2.3e-10

Best Hits

Swiss-Prot: 68% identical to SUBI_SALTY: Sulfate-binding protein (sbp) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02048, sulfate transport system substrate-binding protein (inferred from 97% identity to vap:Vapar_2981)

MetaCyc: 67% identical to sulfate/thiosulfate ABC transporter periplasmic binding protein Sbp (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate and thiosulfate binding protein CysP" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (341 amino acids)

>ABID97_RS15465 sulfate ABC transporter substrate-binding protein (Variovorax sp. OAS795)
MSLRRDFIKLSLGAGVAGAMALAALPSFSQGTAPVTLLNVSYDPTRELYVDYNRAFAKYW
KAKTGQDVTIKQSHGGSGKQARSIIDGIDADVATLALGGDIDALVTHGANVKADWQKRLP
QNSAPYTSTIVFLVKKGNPKGLKDWDDLVKPGVQVITPNPKTSGGARWNYLAAWEFAKRK
YGSDAKAKEYIGSLFKNVPVLDTGARGSTITFVQRGVGDVLLAWENEAFLALKEFGAEKF
EIVVPSISILAEPTVAVVDKVVDKKGTRAVAEEYLKYLYSDEGQDIAGRNFYRPTSEKAK
AKYDKQFPKLTLVTIDQAFGGWAKADKAHFADGGSFDQIYK