Protein Info for ABID97_RS14690 in Variovorax sp. OAS795

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 3 to 364 (362 residues), 400.2 bits, see alignment E=4.6e-124 PF13177: DNA_pol3_delta2" amino acids 21 to 183 (163 residues), 137.4 bits, see alignment E=9.4e-44 PF00004: AAA" amino acids 42 to 176 (135 residues), 35 bits, see alignment E=3.7e-12 PF12169: DNA_pol3_gamma3" amino acids 240 to 372 (133 residues), 77 bits, see alignment E=2.7e-25 PF12170: DNA_pol3_tau_5" amino acids 492 to 609 (118 residues), 52 bits, see alignment E=1.6e-17

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 91% identity to vap:Vapar_2330)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>ABID97_RS14690 DNA polymerase III subunit gamma/tau (Variovorax sp. OAS795)
MSYLVLARKFRPKTFGEMVGQGHVVQALENALTTQRLHHAYLFTGTRGVGKTTVSRILAK
SLNCQGPDGQGGITATPCGVCQACKDIDSGRFVDYTELDAASNRGVDEVQSLLEQSVYKP
VQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSRCLQFNL
RPMAPETVLEHLTSVLQTENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGNGELLET
GVRQMLGSVDRGHVFKLVEALAEGDGRTVVDTSEALRRDGMSAASTLEEMTAVLQAMAVL
QAVPSRAESADSATDPDAADTARLAALMPADETQLLYSLCLHGRAELGLAPDEYAALTMV
LLRLLAFKPSDAAASRASPEKKTLNEAPKASSAAPAVAPVRPAELAVAPVPAAAPGVRSA
VSAPAGQRLAVVSEPVRQSEGRPPALPEVPPWEEAGAKVLAVPMRVQPPPSQRDVPRPDE
QRGPAPPIPPSEDGDFWHATVTQMIAAESISALARELALQSQLVARDVDQWILRVERELL
NQPSAREKLTDALAALGHGVKLAIEIGGVVDSPARRNKQAADERQRVAEEAIRSDPEVQM
LMREFDAKIVPGTLKPA