Protein Info for ABID97_RS14660 in Variovorax sp. OAS795

Annotation: PD-(D/E)XK nuclease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 861 PF12705: PDDEXK_1" amino acids 595 to 843 (249 residues), 121.8 bits, see alignment E=2.5e-39

Best Hits

KEGG orthology group: None (inferred from 90% identity to vap:Vapar_2324)

Predicted SEED Role

"Helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (861 amino acids)

>ABID97_RS14660 PD-(D/E)XK nuclease family protein (Variovorax sp. OAS795)
MNEGHPVQALWCDPAAGVVARIAATIAQRQLHAARTVVLVPYAQLMSVARAMWARCGNPG
FVPRFETTRNWARSAGGFLPAGYDIAFDMAQDLVTAQALLSQAGFAAERFALAGRAVELA
YQLAPLAAAALPEERGSEWAQRAAHVAEAGSESEWFRIESALIRIAVAWAANSGYATDVL
LRDNVRAQVDALIVLEGFQADPLTQTLCTLWADRAVHLSLVPADPRATAPGAHVAADPED
EAELAAACVLRHLAEGRAPVALITTDRALTRRIGAQLQAQGITAHDETGWKLSTTRAAAT
VMSGLRACAHDAGSDQVLDWLKSGADGDAMPVEALEARLRREGVREWSAWCGQAARSEKP
QDIALLPFTEAIEGRRMAMARSRPLAEWLRALRELLAAGGQWEPLAADMAGAKVIGALWL
DADAHGGEDEFPGGRHTLAEFTAWVRDVLEDASFVPPAGNDTPQVVVLPLHQLLGRAFGA
VVIPGCDDRRLPASPEPPGNWSAAQRAELGLPARETLEAAQRAAWGAALCNPCCEILWRQ
SDASGEPVRPSPLVQALQLDHALQPAADPRAPREVALQPTPYPRPSGALLPLRNISTTVY
EDLRRCPYRFFALRQLGLRSADELDAEVDKRDFGNWLHAVLGYFHDALKEKPTDDAEGRL
ALITEAAGHATREFALSDAEFLPFAAAWPAVRDGYLQWLAGHEAGGAVFVESEPWKEQPL
GNLQLVGRLDRIDRMPDGQAFVIDYKTESAAVTKERVKDPTEDTQLAFYAALVADDTLRA
AYVNVGEKSSGTQTVEQTVVVEARDALVAGILDDFARISQGAALPPLGEGAICDYCAARG
LCRKDFWEVEQPSSLAGGLAK