Protein Info for ABID97_RS14625 in Variovorax sp. OAS795

Annotation: phosphate regulon sensor histidine kinase PhoR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 29 to 45 (17 residues), see Phobius details PF11808: PhoR" amino acids 10 to 86 (77 residues), 33.8 bits, see alignment E=1.1e-11 TIGR02966: phosphate regulon sensor kinase PhoR" amino acids 93 to 432 (340 residues), 392.8 bits, see alignment E=5.8e-122 PF00989: PAS" amino acids 96 to 146 (51 residues), 31.8 bits, see alignment 3.8e-11 PF13188: PAS_8" amino acids 97 to 146 (50 residues), 30.9 bits, see alignment 5.8e-11 PF00512: HisKA" amino acids 209 to 273 (65 residues), 73.2 bits, see alignment E=4.4e-24 PF02518: HATPase_c" amino acids 324 to 435 (112 residues), 97.9 bits, see alignment E=1.5e-31

Best Hits

KEGG orthology group: K07636, two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC: 2.7.13.3] (inferred from 94% identity to vpe:Varpa_2495)

Predicted SEED Role

"Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>ABID97_RS14625 phosphate regulon sensor histidine kinase PhoR (Variovorax sp. OAS795)
MPFRIATFLIASIVMGAGAAIIFGWKFGWLGAWLGAALWLALDAWRAERLLRVLRNDAAG
LPTRGAGVWGELSERIRKLLREREQQTRQAEDRLQEFLAAIQASPNGVILLDEQGRIEWC
NQTAASQFGIDAERDLLQHLANLVRDPAFVAYLASWNYSRDVVIDASGPGQAQQRSHPVR
LSVQVHPYAGNRRMLLTRDITALEQAEAMRRDFVANVSHEIRTPLTVLAGFVETLQNLPL
DAQERARYLSLMSQQSHRMETLVNDLLTLSRLEGSAAPSGNQWIRIRALMAQCEDEARGL
SGRLAPLGHDLSFAIEAESEISGAPTELQSAMSNLLSNAIRYTPGGGEVAVSWRLLPDGR
GEYAVRDTGPGIASEHIPRLTERFYRIDRSRSRETGGTGLGLAIVKHIAQRHGAELRIES
TVGKGSRFALVFPATRVREARLLAPR