Protein Info for ABID97_RS13970 in Variovorax sp. OAS795

Annotation: drug/metabolite exporter YedA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 transmembrane" amino acids 22 to 41 (20 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 107 to 130 (24 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 163 to 181 (19 residues), see Phobius details amino acids 192 to 213 (22 residues), see Phobius details amino acids 226 to 247 (22 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 282 to 299 (18 residues), see Phobius details PF00892: EamA" amino acids 22 to 153 (132 residues), 43.9 bits, see alignment E=1.3e-15 amino acids 164 to 298 (135 residues), 67.6 bits, see alignment E=6.3e-23

Best Hits

Swiss-Prot: 40% identical to YEDA_ECOL6: Uncharacterized inner membrane transporter YedA (yedA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 92% identity to vap:Vapar_2135)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>ABID97_RS13970 drug/metabolite exporter YedA (Variovorax sp. OAS795)
MPTLASPAEAAPSAARAALPPILWLCLAATWVVWGSTYLAIKYALVSFAPFLQMGSRFLF
AGVLLAAWMRWRGAAWPSRLQWRNALLVGTLMLGGGMGGTAHAEVTIGSGLVVAFIAVVP
LLIALMNLVWGVKPTGLEAAGIALGLVGVLMLTQGSGFQSSPAGLVAISVACVCWSMGSV
LSQRSLPLAPGAMGFASEMICGGVVLLVLSALSGEELLWPPQPEAAAAWLYLVVFGSLIA
FNAYMVLLARAPAALAASYTFVNPVIAMLLGVWIANETVTRFEWYAVVVILAGVLLLLFK
RSAKA