Protein Info for ABID97_RS13480 in Variovorax sp. OAS795
Annotation: FAD-dependent monooxygenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 57% identity to bge:BC1002_4160)Predicted SEED Role
"Salicylate hydroxylase (EC 1.14.13.1)" in subsystem Salicylate and gentisate catabolism or Salicylate ester degradation (EC 1.14.13.1)
MetaCyc Pathways
- superpathway of salicylate degradation (6/7 steps found)
- methylsalicylate degradation (2/2 steps found)
- salicylate degradation I (1/1 steps found)
- chlorosalicylate degradation (3/7 steps found)
- naphthalene degradation to acetyl-CoA (6/12 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (22/42 steps found)
KEGG Metabolic Maps
- 1- and 2-Methylnaphthalene degradation
- Bile acid biosynthesis
- Fluorene degradation
- Naphthalene and anthracene degradation
Isozymes
Compare fitness of predicted isozymes for: 1.14.13.1
Use Curated BLAST to search for 1.14.13.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (406 amino acids)
>ABID97_RS13480 FAD-dependent monooxygenase (Variovorax sp. OAS795) MPWPSASICNCETTLRNPMRRWQGLNHKHDRKGDTLMNKTQRVLVVGSGIGGATAAYALA KAGLETHCIDIQPARSTLGSGICLLHNTMRALSEIGLAEPCLDSGLRFEVFKQYDAAGQL LMSNPTPPGIGIRRPELARILETSAGEAGAKMERGLTARSVTDRGDHVEVEFSDGREAAY DLVVAADGAYSKLREQFFGAEHRVCFAGQSAWRFNAPRPPEVDGFCLYRSPDGKRAVGAL PTSKETCYLFFLENSAQHLHWPDDQLDVLVRERLAGFSAPVIQDALALITSPQQVLVRPF DVTLVPAPWHRGRVVLIGDSAHSPTPQMTSGGGMAIEDAVVLANCLQAESSIPEALAAYT NRRFERVSTVWNASLQLCKYEQEAVPNPQRSAALLLQTYQYLGQPM