Protein Info for ABID97_RS12605 in Variovorax sp. OAS795

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 PF01590: GAF" amino acids 72 to 206 (135 residues), 38.2 bits, see alignment E=8.1e-13 PF00158: Sigma54_activat" amino acids 356 to 519 (164 residues), 212.6 bits, see alignment E=1.3e-66 PF14532: Sigma54_activ_2" amino acids 368 to 524 (157 residues), 71.6 bits, see alignment E=3.4e-23 PF07728: AAA_5" amino acids 375 to 494 (120 residues), 26.5 bits, see alignment E=2.3e-09 PF01078: Mg_chelatase" amino acids 376 to 493 (118 residues), 21.8 bits, see alignment E=4.4e-08 PF02954: HTH_8" amino acids 637 to 672 (36 residues), 43.7 bits, see alignment 7.2e-15

Best Hits

KEGG orthology group: None (inferred from 93% identity to vap:Vapar_3077)

Predicted SEED Role

"Transcriptional activator of acetoin/glycerol metabolism"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (681 amino acids)

>ABID97_RS12605 sigma-54-dependent Fis family transcriptional regulator (Variovorax sp. OAS795)
MTLTLRQGDRHADRVLDVVRRGFHEEGNDLVTRSWSRCLNQYQLDPGRPREPVIIAASAL
QSRRNQHADVIECARYEMTTLYQQLADAESAVVLTDTDGVIVHMVSSPEFAAEAEPMGLR
AGGMWGEAEAGTNGMGTCLAAAHPISVRREEHFFSQFTQLTCSAVPVFDPSGEIIAVLDV
TSRSSLMQQHVLVLLGMTARMIENRLIDKRFSNAHPLHFHSRPEFVYTLHEGKLAVGDDG
RILAANRSALFQLGLQSMDEIRTQRIDDLFQTSLEDIVQRSLSSSFHPVVAYRANAALRF
FAVARRPASDAATPSRATRAIGAGAAPIVAEAGADAFRAPLRPMPMRAPGVRTFKDARLV
AHLDTARRVVARRTPVLLCGETGSGKEVFARAIHESSPHAEGAFVAVNCASLPETLIESE
LFGYKAGAFTGAQRSGRRGKILQADGGTLFLDEIADMPLELQARLLRVLDERQVTPLGTE
ETHPVDFQLVSASHQHLPSLVRDGRFREDLYYRLAGIELDLPPLRDRSDKRELIHDVLKD
EGGSDSRLGDDAERVLMAYAWPGNLRQLRHVLRSAAALADGKTITREHLPSLAARTAPSP
VSAHAALAAASEAAEASDAVPADAAPAVKLNPIQANERQVLLQMLEQHRWNVSNVAKALD
VSRNTLYRKLHKLHIEISPPD