Protein Info for ABID97_RS11955 in Variovorax sp. OAS795

Annotation: sigma-54 dependent transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 PF00072: Response_reg" amino acids 5 to 110 (106 residues), 68.8 bits, see alignment E=1.5e-22 PF00158: Sigma54_activat" amino acids 141 to 307 (167 residues), 236.9 bits, see alignment E=3.6e-74 PF14532: Sigma54_activ_2" amino acids 142 to 312 (171 residues), 76.5 bits, see alignment E=8.6e-25 PF07728: AAA_5" amino acids 165 to 285 (121 residues), 35 bits, see alignment E=4.9e-12 PF00004: AAA" amino acids 166 to 283 (118 residues), 21.3 bits, see alignment E=1.1e-07 PF02954: HTH_8" amino acids 438 to 478 (41 residues), 38.2 bits, see alignment 3.4e-13

Best Hits

KEGG orthology group: None (inferred from 61% identity to aav:Aave_1901)

Predicted SEED Role

"Nitrogen regulation protein NtrX"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>ABID97_RS11955 sigma-54 dependent transcriptional regulator (Variovorax sp. OAS795)
MGHALIVEDDEDSAKMIAALVAREGHTVMCAHSIGAARKLIAMQRPDLLLLDLHLPDGNG
FDLLHDPDIANDTMLVLMTGQASLETSIKALRLGAADYLVKPINPQHLKGLLKRLIAPSQ
LRAELDEVQELWRETGRFGHLIGRSQPMQRVYRQISRVAGTAVTVFIHGESGTGKELVAR
AVHDLSRRREQPFLAVNCGALSPHLVESEIFGHERGSFTGAERQHQGFFERAHGGTLFLD
EVTEMPLELQVKLLRVLESGTFMRVGSTQVQQTDVRIIAATNRDAAEAVARGKMREDLLY
RLNVFPIALPPLRERGDDIALIAASFLQDLGRQEGGSKRFTPGALARLASHRWPGNVREL
RNVVQRAWVMASGDQIDEEWLPPVEDPGPGAGLRPEPEAAQGPALAPMPPDGHRNGAAAA
ALSGAGENQIVVEVGTQLAEVERRVILATYERCGRHKERTAALLGISMKTLYNRLKEYQQ