Protein Info for ABID97_RS11890 in Variovorax sp. OAS795

Annotation: Gfo/Idh/MocA family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 354 PF01408: GFO_IDH_MocA" amino acids 30 to 145 (116 residues), 71 bits, see alignment E=2.2e-23 PF03447: NAD_binding_3" amino acids 35 to 139 (105 residues), 28.7 bits, see alignment E=2.9e-10 PF02894: GFO_IDH_MocA_C" amino acids 159 to 284 (126 residues), 55.9 bits, see alignment E=8e-19

Best Hits

KEGG orthology group: None (inferred from 80% identity to vpe:Varpa_3057)

Predicted SEED Role

"D-galactose 1-dehydrogenase (EC 1.1.1.48)" (EC 1.1.1.48)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.48

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (354 amino acids)

>ABID97_RS11890 Gfo/Idh/MocA family oxidoreductase (Variovorax sp. OAS795)
MRAPNAMDALGMVPARGAEGESAGRLRKPRLGFLGVGWIGRNRMEAIARDGCAEIAAVAD
ADARTSEAASALAPGALRLDSLDALLDHALDGIVIATPSALHAQQAEAALARGLAVFCQK
PLARTAAETRGVIEAARRANRLLDVDLSYRRTAGMQRIRDLVSAGEIGEVYAVDLVFHNA
YGPDKPWFRDPVLSGGGCVIDLGIHMIDLALWTLGFPRVAAVSSRLHAAGRRLVLPSSSV
VEDHAVAQIDLAGGAVVRLACSWNLPAGRDAVIEASFHGTRGGAAFRNVGGSFYDFVAER
FEGTRTTPLASPPDDWGGRAAVHWARALANGGAFDPRIERLEEVAAVLDAIYER