Protein Info for ABID97_RS09140 in Variovorax sp. OAS795

Annotation: GMP reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01306: guanosine monophosphate reductase
  • amino acids 3 to 313 (311 residues), 539.3 bits, E=2e-166
• PF00478: IMPDH
  • amino acids 5 to 309 (305 residues), 199.8 bits, E=3.3e-63

Best Hits

Swiss-Prot: 97% identical to GUAC_VARPS: GMP reductase (guaC) from Variovorax paradoxus (strain S110)

KEGG orthology group: K00364, GMP reductase [EC: 1.7.1.7] (inferred from 97% identity to vap:Vapar_1534)

Predicted SEED Role

"GMP reductase (EC 1.7.1.7)" in subsystem Purine conversions (EC 1.7.1.7)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.1.7

Protein Sequence (325 amino acids)

>ABID97_RS09140 GMP reductase (Variovorax sp. OAS795)
MQIFDYDNILLLPRKCRVESRSECDASVTLGARSFRLPVVPANMKTVVDEPICLWLAQNG
YFYVMHRFDLDNVKFVREMHGKGVFASISLGVKKPDYETVDQLAAEGLVPEYITIDIAHG
HADSVKNMIGYLKQKLPASFVIAGNVGTPEAVIDLENWGADATKVGIGPGKVCITKLKTG
FGTGGWQLSALKWCARVATKPIIADGGIRDHGDIAKSVRFGASMVMIGSLFAGHEESPGR
TVEVDGALFKEYYGSASDFNKGEYKHVEGKRILEPIKGKLADTLVEMEQDVQSSISYAGG
RTLMDIRKVNYVTLGGDNAGEHLLM