Protein Info for ABID97_RS08920 in Variovorax sp. OAS795

Annotation: SDR family NAD(P)-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF00106: adh_short" amino acids 10 to 196 (187 residues), 204.3 bits, see alignment E=2.1e-64 PF08659: KR" amino acids 12 to 161 (150 residues), 55.4 bits, see alignment E=1.1e-18 PF13561: adh_short_C2" amino acids 15 to 255 (241 residues), 195.4 bits, see alignment E=1.7e-61

Best Hits

Swiss-Prot: 40% identical to YXJF_BACSU: Uncharacterized oxidoreductase YxjF (yxjF) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_1510)

MetaCyc: 42% identical to BadH (Rhodopseudomonas palustris)
R267-RXN

Predicted SEED Role

"D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30)" in subsystem Polyhydroxybutyrate metabolism (EC 1.1.1.30)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.30

Use Curated BLAST to search for 1.1.1.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>ABID97_RS08920 SDR family NAD(P)-dependent oxidoreductase (Variovorax sp. OAS795)
MYANSLTGRHALVTGAARGIGAEIARTLAAEGATLTLLGRDADALRRVAGTLAGQGHGVA
AADVADAQAVQSAFAAARAERGPVAILVNNAGAAESAPFLKTSVELWQRMLSVNLTGSFL
CAQAALPDMLEGGWGRIVNIASTAGQKGYAYVAAYSAAKQGVIGLTRSLALEVARKGITV
NAVCPGYTDTDILRASVANVVGKTGRSEADALAEFSSVNPQRRIVQPAEVADAVRWLCGD
GAASVTGQSVSVSGGEVM