Protein Info for ABID97_RS08915 in Variovorax sp. OAS795

Annotation: ATP-dependent acyl-CoA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 transmembrane" amino acids 264 to 276 (13 residues), see Phobius details PF00501: AMP-binding" amino acids 19 to 379 (361 residues), 194.1 bits, see alignment E=3.5e-61 PF13193: AMP-binding_C" amino acids 430 to 505 (76 residues), 61.8 bits, see alignment E=9.7e-21

Best Hits

KEGG orthology group: K02182, crotonobetaine/carnitine-CoA ligase [EC: 6.2.1.-] (inferred from 86% identity to vpe:Varpa_1664)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.2.1.-

Use Curated BLAST to search for 6.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (533 amino acids)

>ABID97_RS08915 ATP-dependent acyl-CoA ligase (Variovorax sp. OAS795)
MTSSPRTVAAAERTLPDMLRRQAALFGSRPLLRVAGRRWSHADAAEAAGVRAGALAQAGV
RRGDRIAVMCGNRIEFLETFLGAGWLGAATVPVNTASMGPQIGYFLAHSEARLLVIEAGF
LGRLQTTELAQTKLEEIWVIGDEPAAWQPPAGVRMRAYPPGGAAIASARVQPGDPLAILY
TSGTTGPAKGVICPHAQYFWWGVNSAEVLGVGADDVLCTTLPLFHINALNTFAQASLMGA
EVVFETRFSASGFWPSMHANGATVVYLLGAMVPILLAQPAGEAERNHRVRTGLGPGVPEA
AGRAFFERTGVRLLEGYGSTETNFAIATAPHSPRGGVMGWLRPGFQARVADDSDVALPAG
EAGELLLRADEPHAFASGYFNMPDKTVEAWRNLWFHTGDRVVRDADGAFRFVDRIKDAIR
RRGENISSFEVEQVLLSHPGVASCAVYPVQSELAEDEVMAALVPRDGERIDPAELVRFCE
GRLPYFAVPRYIDVLQDLPRTENGKVQKFKLRERGVGTQTWDRGPAARSPAKA