Protein Info for ABID97_RS08885 in Variovorax sp. OAS795

Annotation: aromatic ring-hydroxylating dioxygenase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 PF00355: Rieske" amino acids 42 to 124 (83 residues), 61.4 bits, see alignment E=6.2e-21 PF00848: Ring_hydroxyl_A" amino acids 200 to 400 (201 residues), 40.5 bits, see alignment E=2.9e-14

Best Hits

KEGG orthology group: None (inferred from 93% identity to vap:Vapar_1502)

Predicted SEED Role

"3-phenylpropionate dioxygenase alpha subunit (EC 1.14.1.-)" (EC 1.14.1.-)

Isozymes

Compare fitness of predicted isozymes for: 1.14.1.-

Use Curated BLAST to search for 1.14.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>ABID97_RS08885 aromatic ring-hydroxylating dioxygenase subunit alpha (Variovorax sp. OAS795)
MTSYRHHPDRIAALVQEDRVHRDLYLSDEIFALEQERLFANTWVFLGHASQVPEAGDFVA
QDIAGRPLLMVRQPDGAVHVLYNRCAHKGTQLVTDECGNTGRFFRCPYHAWTYKLDGAPL
GLPLKNGYEGTRLKACESGQGLSVVKHVKVYRDFVFVRLSDTGPSFEDYFGEVLGAIDNM
VDRSPEGKLAVGGGVLRNIVHCNWKMYLENINDTVHPMSTHESATKAAEALWDGHAPTDP
KPMAMEQILPFGSSYEFFDKMGGRVFANGHSVLGVNFSIHSNYAQLPDYEAAMRAAHGEE
RAAEILQRSPQNSVLYPSLSVKGSPQAIRVIRPLAANRTLIEAWSFRAAGAPELLFERAM
SYNRLVFSPMSVVAHDDVHLFESIQQGLRAGGNQWVSLHRNYDPAECAQETVTTNGTNEL
LMRNQFRAWAKAMAVGVEAAP