Protein Info for ABID97_RS08615 in Variovorax sp. OAS795

Annotation: HAMP domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 153 to 177 (25 residues), see Phobius details PF26769: HAMP_PhoQ" amino acids 181 to 226 (46 residues), 27 bits, see alignment 5.2e-10 PF00512: HisKA" amino acids 233 to 294 (62 residues), 31.4 bits, see alignment E=2.3e-11 PF02518: HATPase_c" amino acids 343 to 447 (105 residues), 80.9 bits, see alignment E=1.5e-26

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>ABID97_RS08615 HAMP domain-containing sensor histidine kinase (Variovorax sp. OAS795)
MSALHTLWRRVSEPSLVRRGTGSTLLVFLLIWCALLAYLYAENRKYLAEAPGFQQFGDAL
LVALDETPDPRQARVVMAATERWTAIRRTQDKRLAGIVRYELRDSHGALVYASEGWTGAA
AGGDAYWRYDRTSPHWRLQILNPRRTGSAFLRYNASFILPYLLVAFPFVLLAVWLTVRAS
LRPLQQLARRIEERPSDDLSAVGVPARYRELKPLVQALDTLLLRLRGTVQRERAFVQDAA
HEIRTPLAVINAQAHVLAQATDAAQRAQAEAELNLAIARTSHLAQQLLELAALDRAGTPQ
ASRIDLAHWMRTLLGHAAQAALREGRELSLEAPDTLHGSIDLPAMESVVRNLVDNALRHG
VPGSGIAVSLRIEDGQLLVEVRDDGPGIPEAQRARAFERFHRGGDARASGAGLGLSIVRE
ATLRLGGVVEIVEGLRGRGVGFRVCVPWAAA